葡萄膜炎中的T淋巴细胞亚群
T-lymphocyte subpopulations in uveitis.
作者信息
Murray P I, Dinning W J, Rahi A H
出版信息
Br J Ophthalmol. 1984 Oct;68(10):746-9. doi: 10.1136/bjo.68.10.746.
Abstract
Following an inconclusive study of differential lymphocyte counts in uveitis in which the peripheral blood was examined only once in the course of each case a longitudinal study has been carried out in patients with acute anterior uveitis. Venous blood lymphocytes were examined at intervals throughout the course of the illness, from presentation until six months later. No changes in E-rosetting T cells or total lymphocyte values have been found, nor any variations from normal in the helper (OKT4)/suppressor (OKT8) T-cell ratio. Random studies performed in a sample of patients with heterochromic cyclitis have also failed to reveal consistent abnormalities in peripheral blood lymphocyte parameters.
摘要
在一项关于葡萄膜炎患者淋巴细胞计数差异的研究中，若仅在每个病例病程中对其外周血进行一次检查，结果往往难以定论。因此，针对急性前葡萄膜炎患者开展了一项纵向研究。在疾病全过程中，从患者就诊直至六个月后，定期对外周血淋巴细胞进行检测。结果发现，E-玫瑰花结形成T细胞或淋巴细胞总数均无变化，辅助性（OKT4）/抑制性（OKT8）T细胞比值也未出现任何偏离正常范围的情况。针对异色性睫状体炎患者样本进行的随机研究同样未能揭示外周血淋巴细胞参数存在持续异常。
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