Mesnildrey P, Pavie A, Mussat T, Jault F, Gandjbakhch I, Cabrol C
Arch Mal Coeur Vaiss. 1984 Aug;77(8):917-23.
From 1965 to 1981, 27 patients over 35 years of age were operated for isthmic coarctation of the aorta. Surgery consisted of resection and direct suture in 16 cases, implantation of a Dacron prosthesis in 7 cases, isthmoplasty in 1 case, aortotomy-graft in 1 case, insertion of a Dacron tube between the left subclavian artery and the descending thoracic aorta in 1 case; finally, one patient presented with a rare form of coarctation in a double aortic arch and was treated by a bypass from the brachiocephalic trunk to the descending thoracic aorta. Ten patients had associated pathology. This was treated at the same time in 4 cases: closed heart mitral commissurotomy, cardiac plexectomy, section-suture of patent ductus arteriosus, and a resection of aneurysms of four intercostal arteries. A Bjork aortic valve prosthesis had been inserted nine months previously in a women with calcific aortic stenosis. There were 2 deaths (7,4%) in the immediate postoperative woman with calcific aortic stenosis. There were 2 deaths (7,4%) in the immediate postoperative period (one acute pulmonary oedema, one pulmonary embolism). There has been no operative mortality in the last 10 years. Twenty-three of the 25 survivors have been followed-up for an average period of 91,5 months (range 1 to 18 years). Two patients died of cardiovascular causes. Analysis of these results show: that the mortality rate is not prohibitive compared to that of the natural history of the condition (the average survival rate of unoperated patients is 35 years), good secondary results despite frequent technical difficulties, the possibility of residual hypertension (especially in older patients) which responds well to drug therapy.(ABSTRACT TRUNCATED AT 250 WORDS)
1965年至1981年期间,对27例35岁以上的主动脉峡部缩窄患者进行了手术。手术方式包括:16例行切除并直接缝合,7例行涤纶人工血管植入,1例行峡部成形术,1例行主动脉切开-移植术,1例行在左锁骨下动脉与降胸主动脉之间插入涤纶管;最后,1例患者为双主动脉弓罕见形式的缩窄,采用从头臂干至降胸主动脉的旁路手术治疗。10例患者伴有其他病变。其中4例在手术同时进行了治疗:闭式心脏二尖瓣交界切开术、心脏神经丛切除术、动脉导管未闭切断缝合术以及4条肋间动脉动脉瘤切除术。一名患有钙化性主动脉瓣狭窄的女性在9个月前植入了比约克主动脉瓣人工瓣膜。术后即刻有2例(7.4%)死亡(一名急性肺水肿,一名肺栓塞)。在过去10年中无手术死亡病例。25名幸存者中的23例接受了平均91.5个月(范围1至18年)的随访。2例患者死于心血管疾病。对这些结果的分析表明:与该病自然病程的死亡率相比,手术死亡率并非过高(未手术患者的平均生存率为35岁);尽管存在频繁的技术难题,但术后效果良好;存在残余高血压的可能性(尤其是老年患者),药物治疗对此反应良好。(摘要截选至250字)