促甲状腺激素对胎鼠早期甲状腺碘有机化的体外刺激作用。
TSH stimulation of iodine organification in early foetal rat thyroid in vitro.
作者信息
Pic P, Michel-Bechet M, Bottini J
出版信息
Biol Cell. 1984;51(1):105-8. doi: 10.1111/j.1768-322x.1984.tb00288.x.
Abstract
Thyroid glands from 15 day-old rat foetuses were incubated in Eagle's medium containing Na 125I and supplemented, or not, with TSH for 4 or 24 hours. Electron microscopic radioautographic study shows silver grains mainly in follicular cavities only in the thyroids submitted to TSH during 24 hr. A functional differentiation must therefore take place in thyroid cells under TSH stimulation.
摘要
将15日龄大鼠胎儿的甲状腺在含有Na 125I的伊格尔培养基中培养，添加或不添加促甲状腺激素（TSH），培养4小时或24小时。电子显微镜放射自显影研究表明，银颗粒主要仅在接受24小时促甲状腺激素的甲状腺的滤泡腔内出现。因此，在促甲状腺激素刺激下，甲状腺细胞必定发生了功能分化。
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