• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Olfactory tubercle choline acetyltransferase activity in Alzheimer-type dementia, Down's syndrome and Huntington's chorea.阿尔茨海默型痴呆、唐氏综合征和亨廷顿舞蹈病中嗅结节胆碱乙酰转移酶活性
J Neurol Neurosurg Psychiatry. 1984 Oct;47(10):1138-9. doi: 10.1136/jnnp.47.10.1138-a.
2
Regional distribution of choline acetyltransferase in the human brain: changes in Huntington's chorea.胆碱乙酰转移酶在人脑内的区域分布：亨廷顿舞蹈病中的变化
J Neurol Neurosurg Psychiatry. 1975 Jul;38(7):669-77. doi: 10.1136/jnnp.38.7.669.
3
Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and Down's syndrome.早老性和老年性阿尔茨海默型痴呆及唐氏综合征中的儿茶酚胺和胆碱能酶
Brain Res. 1983 Nov 28;280(1):119-26. doi: 10.1016/0006-8993(83)91179-4.
4
Cholinergic enzymes in the spinal cord in Alzheimer-type dementia.阿尔茨海默型痴呆患者脊髓中的胆碱能酶
J Neural Transm Park Dis Dement Sect. 1989;1(4):311-5. doi: 10.1007/BF02263485.
5
Alzheimer-like cholinergic deficiency in Down syndrome.
Lancet. 1980 Nov 1;2(8201):979. doi: 10.1016/s0140-6736(80)92137-6.
6
Alzheimer's disease: choline acetyltransferase activity in brain tissue from clinical and pathological subgroups.阿尔茨海默病：临床和病理亚组脑组织中的胆碱乙酰转移酶活性
Ann Neurol. 1983 Sep;14(3):284-93. doi: 10.1002/ana.410140306.
7
Biochemistry of Dementias.痴呆症的生物化学
Proc R Soc Med. 1977 May;70(5):351-3. doi: 10.1177/003591577707000514.
8
Choline acetyltransferase activity at different ages in brain of Ts65Dn mice, an animal model for Down's syndrome and related neurodegenerative diseases.Ts65Dn小鼠大脑中不同年龄的胆碱乙酰转移酶活性，Ts65Dn小鼠是唐氏综合征及相关神经退行性疾病的动物模型。
J Neurochem. 2006 Apr;97(2):515-26. doi: 10.1111/j.1471-4159.2006.03769.x. Epub 2006 Mar 15.
9
Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain.亨廷顿病和阿尔茨海默病大脑中丙酮酸脱氢酶复合物活性降低。
Ann Neurol. 1983 Jan;13(1):72-8. doi: 10.1002/ana.410130116.
10
Transneuronal effects of olfactory bulb removal on choline acetyltransferase and glutamic acid decarboxylase activities in the olfactory tubercle.嗅球切除对嗅结节中胆碱乙酰转移酶和谷氨酸脱羧酶活性的跨神经元效应。
Brain Res. 1979 Dec 7;178(1):185-90. doi: 10.1016/0006-8993(79)90098-2.

引用本文的文献

1
An experimental framework for conjoint measures of olfaction, navigation, and motion as pre-clinical biomarkers of Alzheimer's disease.作为阿尔茨海默病临床前生物标志物的嗅觉、导航和运动联合测量的实验框架。
J Alzheimers Dis Rep. 2024 Dec 23;8(1):1722-1744. doi: 10.1177/25424823241307617. eCollection 2024.
2
Ursolic acid and its isomer oleanolic acid are responsible for the anti-dementia effects of Ocimum sanctum in olfactory bulbectomized mice.熊果酸及其异构体齐墩果酸是圣罗勒（Ocimum sanctum）对嗅球切除小鼠抗痴呆作用的原因。
J Nat Med. 2022 Jun;76(3):621-633. doi: 10.1007/s11418-022-01609-2. Epub 2022 Feb 26.
3
Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment.人类嗅球前嗅核中 Caspase-6 活性的增加与认知障碍有关。
Acta Neuropathol Commun. 2016 Dec 8;4(1):127. doi: 10.1186/s40478-016-0400-x.
4
The Habituation/Cross-Habituation Test Revisited: Guidance from Sniffing and Video Tracking.重新审视习惯化/交叉习惯化测试：来自嗅觉和视频追踪的指导
Neural Plast. 2016;2016:9131284. doi: 10.1155/2016/9131284. Epub 2016 Jul 19.
5
Olfaction in dementia.痴呆中的嗅觉
J Neurol Neurosurg Psychiatry. 1985 Aug;48(8):848-9. doi: 10.1136/jnnp.48.8.848-c.
6
Olfactory threshold in Parkinson's disease.帕金森病的嗅觉阈值
J Neurol Neurosurg Psychiatry. 1987 Jan;50(1):88-9. doi: 10.1136/jnnp.50.1.88.
7
Olfactory bulb changes in Alzheimer's disease.阿尔茨海默病中的嗅球变化。
Acta Neuropathol. 1987;73(4):365-9. doi: 10.1007/BF00688261.
8
Pathogenesis of Alzheimer's disease--beyond the cholinergic hypothesis: discussion paper.阿尔茨海默病的发病机制——超越胆碱能假说：讨论文件
J R Soc Med. 1986 Jun;79(6):347-52. doi: 10.1177/014107688607900612.
9
Selective loss of cholinergic neurons in the ventral striatum of patients with Alzheimer disease.阿尔茨海默病患者腹侧纹状体胆碱能神经元的选择性丧失。
Proc Natl Acad Sci U S A. 1989 Nov;86(21):8580-4. doi: 10.1073/pnas.86.21.8580.

本文引用的文献

1
The olfactory bulbs in Alzheimer's disease.阿尔茨海默病中的嗅球。
J Neurol Neurosurg Psychiatry. 1984 Jan;47(1):56-60. doi: 10.1136/jnnp.47.1.56.
2
Two new lesions in Alzheimer's disease.阿尔茨海默病中的两个新病变。
Lancet. 1983 Nov 19;2(8360):1203. doi: 10.1016/s0140-6736(83)91256-4.
3
Alzheimer-like cholinergic deficiency in Down syndrome.
Lancet. 1980 Nov 1;2(8201):979. doi: 10.1016/s0140-6736(80)92137-6.
4
Neurochemical alterations in Huntington's chorea: a study of post-mortem brain tissue.亨廷顿舞蹈症的神经化学改变：一项对死后脑组织的研究。
Brain. 1980 Mar;103(1):179-210. doi: 10.1093/brain/103.1.179.
5
A rapid radiochemical method for the determination of choline acetyltransferase.一种用于测定胆碱乙酰转移酶的快速放射化学方法。
J Neurochem. 1975 Feb;24(2):407-9. doi: 10.1111/j.1471-4159.1975.tb11895.x.
6
Neurotransmitter-related enzymes in senile dementia of the Alzheimer type.阿尔茨海默型老年痴呆症中的神经递质相关酶
Brain Res. 1979 Aug 3;171(2):319-27. doi: 10.1016/0006-8993(79)90336-6.
7
Regional distribution of enzymes associated with neurotransmission by monoamines, acetylcholine and GABA in the human brain.单胺、乙酰胆碱和γ-氨基丁酸在人脑中与神经传递相关的酶的区域分布。
J Neurochem. 1978 Apr;30(4):827-39. doi: 10.1111/j.1471-4159.1978.tb10791.x.

Olfactory tubercle choline acetyltransferase activity in Alzheimer-type dementia, Down's syndrome and Huntington's chorea.

作者信息

Simpson J, Yates C M, Gordon A, St Clair D M

出版信息

J Neurol Neurosurg Psychiatry. 1984 Oct;47(10):1138-9. doi: 10.1136/jnnp.47.10.1138-a.

DOI:10.1136/jnnp.47.10.1138-a
PMID:6239011
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1028050/
Abstract
摘要