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Studies on the biosynthesis of bialaphos (SF-1293). 4. Production of phosphonic acid derivatives, 2-hydroxyethylphosphonic acid, hydroxymethylphosphonic acid and phosphonoformic acid by blocked mutants of Streptomyces hygroscopicus SF-1293 and their roles in the biosynthesis of bialaphos.

作者信息

Imai S, Seto H, Sasaki T, Tsuruoka T, Ogawa H, Satoh A, Inouye S, Niida T, Otake N

出版信息

J Antibiot (Tokyo). 1984 Nov;37(11):1505-8. doi: 10.7164/antibiotics.37.1505.

DOI:10.7164/antibiotics.37.1505
PMID:6239850
Abstract
摘要

相似文献

1
Studies on the biosynthesis of bialaphos (SF-1293). 4. Production of phosphonic acid derivatives, 2-hydroxyethylphosphonic acid, hydroxymethylphosphonic acid and phosphonoformic acid by blocked mutants of Streptomyces hygroscopicus SF-1293 and their roles in the biosynthesis of bialaphos.
J Antibiot (Tokyo). 1984 Nov;37(11):1505-8. doi: 10.7164/antibiotics.37.1505.
2
Studies on the biosynthesis of bialaphos (SF-1293). 6. Production of N-acetyl-demethylphosphinothricin and N-acetylbialaphos by blocked mutants of Streptomyces hygroscopicus SF-1293 and their roles in the biosynthesis of bialaphos.双丙氨膦（SF - 1293）的生物合成研究。6. 吸水链霉菌SF - 1293阻断突变体产生N - 乙酰去甲基膦丝菌素和N - 乙酰双丙氨膦及其在双丙氨膦生物合成中的作用。
J Antibiot (Tokyo). 1985 May;38(5):687-90. doi: 10.7164/antibiotics.38.687.
3
Studies on the biosynthesis of bialaphos (SF-1293). 5. Production of 2-phosphinomethylmalic acid, an analogue of citric acid by Streptomyces hygroscopicus SF-1293 and its involvement in the biosynthesis of bialaphos.
J Antibiot (Tokyo). 1984 Nov;37(11):1509-11. doi: 10.7164/antibiotics.37.1509.
4
Studies on the biosynthesis of bialaphos (SF-1293) Part 3. Production of phosphinic acid derivatives, MP-103, MP-104 and MP-105, by a blocked mutant of Streptomyces hygroscopicus SF-1293 and their roles in the biosynthesis of bialaphos.双丙氨膦（SF - 1293）的生物合成研究 第3部分。吸水链霉菌SF - 1293的一个阻断突变体产生次膦酸衍生物MP - 103、MP - 104和MP - 105及其在双丙氨膦生物合成中的作用。
Biochem Biophys Res Commun. 1983 Mar 29;111(3):1008-14. doi: 10.1016/0006-291x(83)91400-6.
5
The bialaphos biosynthetic genes of Streptomyces hygroscopicus: cloning and analysis of the genes involved in the alanylation step.吸水链霉菌双丙氨膦生物合成基因：丙氨酰化步骤相关基因的克隆与分析
J Antibiot (Tokyo). 1988 Apr;41(4):538-47. doi: 10.7164/antibiotics.41.538.
6
Studies on the biosynthesis of bialaphos (SF-1293). 14. Nucleotide sequence of phosphoenolpyruvate phosphomutase gene isolated from a bialaphos producing organism, Streptomyces hygroscopicus, and its expression in Streptomyces lividans.双丙氨膦（SF-1293）的生物合成研究。14. 从双丙氨膦产生菌吸水链霉菌中分离的磷酸烯醇丙酮酸磷酸变位酶基因的核苷酸序列及其在淡紫链霉菌中的表达。
J Antibiot (Tokyo). 1992 Dec;45(12):1977-80. doi: 10.7164/antibiotics.45.1977.
7
Studies on the biosynthesis of bialaphos (SF-1293) 12. C-P bond formation mechanism of bialaphos: discovery of a P-methylation enzyme.双丙氨膦（SF - 1293）生物合成的研究12. 双丙氨膦的C - P键形成机制：一种P - 甲基化酶的发现
J Antibiot (Tokyo). 1992 May;45(5):781-7. doi: 10.7164/antibiotics.45.781.
8
The bialaphos resistance gene (bar) plays a role in both self-defense and bialaphos biosynthesis in Streptomyces hygroscopicus.双丙氨膦抗性基因（bar）在吸水链霉菌的自我防御和双丙氨膦生物合成中均发挥作用。
J Antibiot (Tokyo). 1988 Dec;41(12):1838-45. doi: 10.7164/antibiotics.41.1838.
9
Biochemical mechanisms of C-P bond formation of bialaphos: use of gene manipulation for the analysis of the C-P bond formation step.双丙氨膦中C-P键形成的生化机制：利用基因操作分析C-P键形成步骤
Agric Biol Chem. 1990 Aug;54(8):2121-5.
10
Bialaphos.
Biotechnology. 1995;28:197-222. doi: 10.1016/b978-0-7506-9095-9.50014-9.

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Enzymatic kinetic resolution of desmethylphosphinothricin indicates that phosphinic group is a bioisostere of carboxyl group.去甲基草丁膦的酶促动力学拆分表明，次膦酸基团是羧基的生物电子等排体。
Commun Chem. 2020 Sep 2;3(1):121. doi: 10.1038/s42004-020-00368-z.
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Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide.抗生素草丁膦三肽生物合成中的异常转变。
Nat Chem Biol. 2007 Aug;3(8):480-5. doi: 10.1038/nchembio.2007.9. Epub 2007 Jul 15.
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Characterization of the herbicide-resistance gene bar from Streptomyces hygroscopicus.
从吸水链霉菌中鉴定出除草剂抗性基因 bar。
EMBO J. 1987 Sep;6(9):2519-23. doi: 10.1002/j.1460-2075.1987.tb02538.x.
4
Molecular cloning, sequence analysis, and heterologous expression of the phosphinothricin tripeptide biosynthetic gene cluster from Streptomyces viridochromogenes DSM 40736.来自绿色产色链霉菌DSM 40736的草丁膦三肽生物合成基因簇的分子克隆、序列分析及异源表达
Antimicrob Agents Chemother. 2005 Jan;49(1):230-40. doi: 10.1128/AAC.49.1.230-240.2005.
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Transcriptional regulation of bialaphos biosynthesis in Streptomyces hygroscopicus.吸水链霉菌中双丙氨膦生物合成的转录调控
J Bacteriol. 1987 Aug;169(8):3482-8. doi: 10.1128/jb.169.8.3482-3488.1987.
6
Carboxyphosphonoenolpyruvate phosphonomutase, a novel enzyme catalyzing C-P bond formation.羧基膦酰烯醇丙酮酸膦酸变位酶，一种催化碳-磷键形成的新型酶。
J Bacteriol. 1990 Jun;172(6):3066-72. doi: 10.1128/jb.172.6.3066-3072.1990.