双丙氨膦（SF - 1293）的生物合成研究。6. 吸水链霉菌SF - 1293阻断突变体产生N - 乙酰去甲基膦丝菌素和N - 乙酰双丙氨膦及其在双丙氨膦生物合成中的作用。 - Suppr

Suppr

超能文献

Studies on the biosynthesis of bialaphos (SF-1293). 6. Production of N-acetyl-demethylphosphinothricin and N-acetylbialaphos by blocked mutants of Streptomyces hygroscopicus SF-1293 and their roles in the biosynthesis of bialaphos.

作者信息

Imai S, Seto H, Sasaki T, Tsuruoka T, Ogawa H, Satoh A, Inouye S, Niida T, Otake N

出版信息

J Antibiot (Tokyo). 1985 May;38(5):687-90. doi: 10.7164/antibiotics.38.687.

DOI:10.7164/antibiotics.38.687

PMID:4019315

Abstract

摘要

相似文献

Studies on the biosynthesis of bialaphos (SF-1293). 6. Production of N-acetyl-demethylphosphinothricin and N-acetylbialaphos by blocked mutants of Streptomyces hygroscopicus SF-1293 and their roles in the biosynthesis of bialaphos.双丙氨膦（SF - 1293）的生物合成研究。6. 吸水链霉菌SF - 1293阻断突变体产生N - 乙酰去甲基膦丝菌素和N - 乙酰双丙氨膦及其在双丙氨膦生物合成中的作用。

J Antibiot (Tokyo). 1985 May;38(5):687-90. doi: 10.7164/antibiotics.38.687.

Studies on the biosynthesis of bialaphos (SF-1293). 5. Production of 2-phosphinomethylmalic acid, an analogue of citric acid by Streptomyces hygroscopicus SF-1293 and its involvement in the biosynthesis of bialaphos.

J Antibiot (Tokyo). 1984 Nov;37(11):1509-11. doi: 10.7164/antibiotics.37.1509.

The bialaphos biosynthetic genes of Streptomyces hygroscopicus: cloning and analysis of the genes involved in the alanylation step.吸水链霉菌双丙氨膦生物合成基因：丙氨酰化步骤相关基因的克隆与分析

J Antibiot (Tokyo). 1988 Apr;41(4):538-47. doi: 10.7164/antibiotics.41.538.

Studies on the biosynthesis of bialaphos (SF-1293). 4. Production of phosphonic acid derivatives, 2-hydroxyethylphosphonic acid, hydroxymethylphosphonic acid and phosphonoformic acid by blocked mutants of Streptomyces hygroscopicus SF-1293 and their roles in the biosynthesis of bialaphos.

J Antibiot (Tokyo). 1984 Nov;37(11):1505-8. doi: 10.7164/antibiotics.37.1505.

The bialaphos resistance gene (bar) plays a role in both self-defense and bialaphos biosynthesis in Streptomyces hygroscopicus.双丙氨膦抗性基因（bar）在吸水链霉菌的自我防御和双丙氨膦生物合成中均发挥作用。

J Antibiot (Tokyo). 1988 Dec;41(12):1838-45. doi: 10.7164/antibiotics.41.1838.

Studies on the biosynthesis of bialaphos (SF-1293) Part 3. Production of phosphinic acid derivatives, MP-103, MP-104 and MP-105, by a blocked mutant of Streptomyces hygroscopicus SF-1293 and their roles in the biosynthesis of bialaphos.双丙氨膦（SF - 1293）的生物合成研究第3部分。吸水链霉菌SF - 1293的一个阻断突变体产生次膦酸衍生物MP - 103、MP - 104和MP - 105及其在双丙氨膦生物合成中的作用。

Biochem Biophys Res Commun. 1983 Mar 29;111(3):1008-14. doi: 10.1016/0006-291x(83)91400-6.

Studies on the biosynthesis of bialaphos (SF-1293). 14. Nucleotide sequence of phosphoenolpyruvate phosphomutase gene isolated from a bialaphos producing organism, Streptomyces hygroscopicus, and its expression in Streptomyces lividans.双丙氨膦（SF-1293）的生物合成研究。14. 从双丙氨膦产生菌吸水链霉菌中分离的磷酸烯醇丙酮酸磷酸变位酶基因的核苷酸序列及其在淡紫链霉菌中的表达。

J Antibiot (Tokyo). 1992 Dec;45(12):1977-80. doi: 10.7164/antibiotics.45.1977.

Studies on the biosynthesis of bialaphos (SF-1293). 1. Incorporation of 13C- and 2H-labeled precursors into bialaphos.双丙氨膦（SF - 1293）的生物合成研究。1. 将13C和2H标记的前体掺入双丙氨膦中。

J Antibiot (Tokyo). 1982 Dec;35(12):1719-21. doi: 10.7164/antibiotics.35.1719.

Studies on the biosynthesis of bialaphos (SF-1293) 12. C-P bond formation mechanism of bialaphos: discovery of a P-methylation enzyme.双丙氨膦（SF - 1293）生物合成的研究12. 双丙氨膦的C - P键形成机制：一种P - 甲基化酶的发现

J Antibiot (Tokyo). 1992 May;45(5):781-7. doi: 10.7164/antibiotics.45.781.

Transcriptional regulation of bialaphos biosynthesis in Streptomyces hygroscopicus.吸水链霉菌中双丙氨膦生物合成的转录调控

J Bacteriol. 1987 Aug;169(8):3482-8. doi: 10.1128/jb.169.8.3482-3488.1987.

引用本文的文献

Enzymatic Synthesis of Biologically Active -Phosphinic Analogue of α-Ketoglutarate.生物活性α-酮戊二酸次膦酸类似物的酶促合成

Biomolecules. 2024 Dec 10;14(12):1574. doi: 10.3390/biom14121574.

Integrated multi-omics unveil the impact of H-phosphinic analogs of glutamate and α-ketoglutarate on Escherichia coli metabolism.整合多组学揭示 H-膦酸酯类似物谷氨酸和 α-酮戊二酸对大肠杆菌代谢的影响。

J Biol Chem. 2024 Oct;300(10):107803. doi: 10.1016/j.jbc.2024.107803. Epub 2024 Sep 21.

A Desmethylphosphinothricin Dipeptide Derivative Effectively Inhibits and Growth.一种去甲基膦丝氨酸二肽衍生物能有效抑制和生长。

Biomolecules. 2023 Sep 26;13(10):1451. doi: 10.3390/biom13101451.

Enzymatic kinetic resolution of desmethylphosphinothricin indicates that phosphinic group is a bioisostere of carboxyl group.去甲基草丁膦的酶促动力学拆分表明，次膦酸基团是羧基的生物电子等排体。

Commun Chem. 2020 Sep 2;3(1):121. doi: 10.1038/s42004-020-00368-z.

Conserved biosynthetic pathways for phosalacine, bialaphos and newly discovered phosphonic acid natural products.膦丝菌素、双丙氨膦及新发现的膦酸天然产物的保守生物合成途径。

J Antibiot (Tokyo). 2016 Jan;69(1):15-25. doi: 10.1038/ja.2015.77. Epub 2015 Sep 2.

Spectroscopic characterization and mechanistic investigation of P-methyl transfer by a radical SAM enzyme from the marine bacterium Shewanella denitrificans OS217.对来自反硝化希瓦氏菌OS217的一种自由基S-腺苷甲硫氨酸酶进行的P-甲基转移的光谱表征及机理研究。

Biochim Biophys Acta. 2014 Dec;1844(12):2135-44. doi: 10.1016/j.bbapap.2014.09.009. Epub 2014 Sep 16.

Avoidance of suicide in antibiotic-producing microbes.避免抗生素产生菌的自杀行为。

J Ind Microbiol Biotechnol. 2010 Jul;37(7):643-72. doi: 10.1007/s10295-010-0721-x. Epub 2010 May 6.

Biosynthesis of phosphonic and phosphinic acid natural products.膦酸和次膦酸天然产物的生物合成。

Annu Rev Biochem. 2009;78:65-94. doi: 10.1146/annurev.biochem.78.091707.100215.

In vitro characterization of a heterologously expressed nonribosomal Peptide synthetase involved in phosphinothricin tripeptide biosynthesis.参与草铵膦三肽生物合成的异源表达非核糖体肽合成酶的体外特性分析。

Biochemistry. 2009 Jun 16;48(23):5054-6. doi: 10.1021/bi900164d.

Characterization of the herbicide-resistance gene bar from Streptomyces hygroscopicus.从吸水链霉菌中鉴定出除草剂抗性基因 bar。

EMBO J. 1987 Sep;6(9):2519-23. doi: 10.1002/j.1460-2075.1987.tb02538.x.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验