Simmons M, Tucker A K
Clin Radiol. 1978 Jan;29(1):47-52. doi: 10.1016/s0009-9260(78)80163-9.
Rhabdomyosarcoma usually presents as a soft tissue mass, which may invade adjacent bone. However, the patient presents occasionally with bony metastases. Recognition of these is important for staging and management. Fifty-eight cases have been reviewed; 14 of these had local bone invasion by the soft tissue tumour. All bones involvel were flat bones; 12 showed permeated bone destruction and two showed geographic destruction. Bone expansion was seen in half the involved bones. Twelve of the 58 cases showed secondary bone deposits, which were the presenting feature in five. Although 10 cases had permeated bone destruction, two were very well defined with a wide range of radiological appearances. The radiological differential diagnosis includes neuroblastoma, leukaemic infiltration, lymphoma, histiocytosis X, solitary and multifocal osteosarcoma and other deposits.
横纹肌肉瘤通常表现为软组织肿块，可能侵犯相邻骨骼。然而，患者偶尔会出现骨转移。认识到这些对于分期和治疗很重要。回顾了58例病例；其中14例软组织肿瘤有局部骨侵犯。所有受累骨骼均为扁骨；12例表现为弥漫性骨质破坏，2例表现为地图样破坏。一半受累骨骼可见骨质膨胀。58例中有12例显示继发性骨转移，其中5例以此为首发表现。虽然10例有弥漫性骨质破坏，但其中2例边界非常清晰，有多种影像学表现。影像学鉴别诊断包括神经母细胞瘤、白血病浸润、淋巴瘤、组织细胞增多症X、孤立性和多灶性骨肉瘤及其他转移瘤。
