Sorenson A W, Rosenshein N, Tepper S A, Kritchevsky D
J Med. 1984;15(5-6):409-15.
The levels of total serum hexosaminidase and of its heat stable isozyme (beta-hexosaminidase) were determined in the sera of subjects bearing ovarian and other female genital cancers and of control subjects. The assays were carried out on a double blind basis. Total hexosaminidase levels were significantly elevated in sera of subjects with female genital cancers and in subjects with ovarian cancer. Levels of beta-hexosaminidase were elevated in all subjects with genital cancer. The hexosaminidase assay may be a convenient biomarker for human cancer since earlier studies have shown that total and beta-hexosaminidase levels are elevated in sera of most cancer patients studied.
测定了患有卵巢癌和其他女性生殖系统癌症的受试者以及对照受试者血清中总血清己糖胺酶及其热稳定同工酶（β-己糖胺酶）的水平。检测是在双盲基础上进行的。患有女性生殖系统癌症的受试者以及患有卵巢癌的受试者血清中总己糖胺酶水平显著升高。所有患有生殖系统癌症的受试者β-己糖胺酶水平均升高。己糖胺酶检测可能是一种方便的人类癌症生物标志物，因为早期研究表明，在大多数所研究的癌症患者血清中，总己糖胺酶和β-己糖胺酶水平都会升高。
