Verrucous carcinoma.

The various clinicopathologic forms of verrucous carcinoma of skin and mucous membrane are reviewed. It is found that the histology and natural history of these well differentiated types of squamous cell carcinoma are remarkably similar. It is concluded that verrucous carcinomas of the head and neck, giant condyloma acuminatum of the genitalia, and carcinoma cuniculatum of the lower extremity are but variants of the same neoplastic system.