Filizzolo F, D'angelo V, Collice M, Ferrara M, Donati M B, Porta M
Eur Neurol. 1978;17(1):43-7. doi: 10.1159/000114920.
10 patients suffering from intracranial aneurysm causing subarachnoid hemorrhage (SAH) have been treated during the acute pre-and postoperatory phase with omega-aminocaproic acid. The blood and the cerebrospinal fluid of the treated patients have been analyzed in order to study fibrin(ogen) degradation products (FDP) and fibrinolytic activity (FA). The results so obtained show only an alteration of local fibrinolytic processes either inside or around the aneurysmatic clot: there were no alterations of the systemic FA. Furthermore, monitoring of FDP and FA was a very useful tool in those patients who took advantage of the treatment with omega-aminocaproic acid which protected them from rebleeding.
10例因颅内动脉瘤导致蛛网膜下腔出血（SAH）的患者在急性术前和术后阶段接受了氨甲环酸治疗。为了研究纤维蛋白（原）降解产物（FDP）和纤溶活性（FA），对接受治疗患者的血液和脑脊液进行了分析。所获得的结果表明，仅在动脉瘤血栓内部或周围存在局部纤溶过程的改变：全身FA没有改变。此外，对于那些受益于氨甲环酸治疗从而预防再出血的患者，监测FDP和FA是一种非常有用的工具。
