Dehner L P, Chen K T
Arch Otolaryngol. 1980 Jan;106(1):13-9. doi: 10.1001/archotol.1980.00790250015004.
Glandular neoplasms represented 14% of primary tumors of the external and middle ear at the University of Minnesota. Although the collective term "ceruminoma" has been used in the past, four distinctive histopathologic patterns were recognized among our 12 cases: adenoma (four cases), pleomorphic adenoma (one case), adenoid cystic carcinoma (two cases) and adenocarcinoma (five cases). The prognosis correlated with these subgroups. A thorough review of the English literature also tended to support the rationale for the subclassification of so-called ceruminomas. The prevailing histogenetic view is that these tumors are derived from the modified apocrine glands of the auditory canal, the ceruminous glands. In some instances, these tumors may originate from ectopic salivary gland tissue.
在明尼苏达大学,腺体肿瘤占外耳和中耳原发性肿瘤的14%。尽管过去曾使用“耵聍瘤”这一统称,但在我们的12例病例中识别出了四种独特的组织病理学模式:腺瘤(4例)、多形性腺瘤(1例)、腺样囊性癌(2例)和腺癌(5例)。预后与这些亚组相关。对英文文献的全面回顾也倾向于支持对所谓耵聍瘤进行亚分类的理论依据。目前流行的组织发生学观点是,这些肿瘤起源于耳道的变形顶泌腺,即耵聍腺。在某些情况下,这些肿瘤可能起源于异位唾液腺组织。