Ohama K, Kusumi I, Takahara H, Kajii T
Hum Genet. 1978 Jan 19;40(2):221-5. doi: 10.1007/BF00272305.
A family with five induced and seven spontaneous abortions and no live births is described. Four of the seven spontaneous abortuses were available for cytogenetic examination and three were successfully karyotyped. Their karyotypes were 46,XX; 46,XX/46,XX,t(2;2)(2p2p;2q2q); and 46,XY. The karyotypes of the parents were normal. The origin of the 2p/2p and 2q/2q translocation in one of the abortuses was assigned to an interhomologous whole-arm translocation in an early mitotic division in a conceptus with a 46,XX karyotype.
本文描述了一个有5次人工流产和7次自然流产且无存活婴儿出生的家庭。7次自然流产中有4次可用于细胞遗传学检查，其中3次成功进行了核型分析。它们的核型分别为46,XX；46,XX/46,XX,t(2;2)(2p2p;2q2q)；以及46,XY。父母的核型正常。其中一次流产胎儿中2p/2p和2q/2q易位的起源被认为是在一个核型为46,XX的孕体早期有丝分裂中发生的同源全臂易位。
