Whole-arm translocation between homologous chromosomes 7 in a woman with successive spontaneous abortions.

Whole-arm translocation between homologous chromosomes 7 in a woman with four successive spontaneous abortions is reported. All of the metaphases in cultured lymphocytes, skin fibroblasts, and decidual cells from the latest abortion specimen revealed the translocation. It was deduced that the translocation occurred during the period between the second meiotic division and the first mitotic division.