石蜡包埋眼黑色素瘤的红细胞沉降率研究
ESR investigation of paraffin-embedded ocular melanomas.
作者信息
Elek G, Lapis K, Rockenbauer A
出版信息
Br J Cancer. 1980 Feb;41(2):199-203. doi: 10.1038/bjc.1980.30.
Abstract
Ocular melanomas embedded in paraffin wax for histological examination have been studied by electron spin resonance (ESR) spectroscopy. A free-radical signal was detected at the g = 2.003 section of the spectrum. The amplitude of this signal was correlated with the number of melanin granules in microscopical slides made from the tumour. This positive correlation can make ESR spectroscopy suitable for estimating the melanin content in the embedded melanoma blocks. Additional paramagnetic signals can also be detected. The clarification of their significance needs, however, further ESR measurements.
摘要
已通过电子自旋共振（ESR）光谱法对包埋在石蜡中用于组织学检查的眼部黑色素瘤进行了研究。在光谱的g = 2.003处检测到自由基信号。该信号的幅度与由肿瘤制成的显微镜载玻片上黑色素颗粒的数量相关。这种正相关关系使得ESR光谱法适用于估计包埋的黑色素瘤块中的黑色素含量。还可以检测到其他顺磁信号。然而，要阐明它们的意义还需要进一步的ESR测量。
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