• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

质粒的消除与海水鱼类病原菌鳗弧菌的毒力减弱相关。

Curing of a plasmid is correlated with an attenuation of virulence in the marine fish pathogen Vibrio anguillarum.

作者信息

Crosa J H, Hodges L L, Schiewe M H

出版信息

Infect Immun. 1980 Mar;27(3):897-902. doi: 10.1128/iai.27.3.897-902.1980.

DOI:10.1128/iai.27.3.897-902.1980
PMID:6247282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC550859/
Abstract

The transposon A sequence Tn1 containing the ampicillin resistance determinants was transposed from RP4 to a plasmid of the marine fish pathogen Vibrio anguillarum. Curing experiments in which plasmid loss was determined by analysis of the segregation of the ampicillin resistance phenotype showed the association of virulence with the specific V. anguillarum plasmid class.

摘要

携带氨苄青霉素抗性决定簇的转座子A序列Tn1从RP4转座到海洋鱼类病原菌鳗弧菌的一个质粒上。通过分析氨苄青霉素抗性表型的分离来确定质粒丢失的消除实验表明，毒力与鳗弧菌特定的质粒类别有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db33/550859/d9bb151361a6/iai00171-0194-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db33/550859/d90f03e858c2/iai00171-0193-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db33/550859/d9bb151361a6/iai00171-0194-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db33/550859/d90f03e858c2/iai00171-0193-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db33/550859/d9bb151361a6/iai00171-0194-a.jpg

相似文献

1
Curing of a plasmid is correlated with an attenuation of virulence in the marine fish pathogen Vibrio anguillarum.质粒的消除与海水鱼类病原菌鳗弧菌的毒力减弱相关。
Infect Immun. 1980 Mar;27(3):897-902. doi: 10.1128/iai.27.3.897-902.1980.
2
Complete genome sequence of the marine fish pathogen Vibrio anguillarum and genome-wide transposon mutagenesis analysis of genes essential for in vivo infection.海洋鱼类病原体鳗弧菌的全基因组序列和对体内感染必需基因的全基因组转座子诱变分析。
Microbiol Res. 2018 Nov;216:97-107. doi: 10.1016/j.micres.2018.08.011. Epub 2018 Aug 24.
3
A plasmid associated with virulence in the marine fish pathogen Vibrio anguillarum specifies an iron-sequestering system.与海洋鱼类病原体鳗弧菌毒力相关的一种质粒规定了一种铁螯合系统。
Nature. 1980 Apr 10;284(5756):566-8. doi: 10.1038/284566a0.
4
Chemotactic motility is required for invasion of the host by the fish pathogen Vibrio anguillarum.趋化运动是鱼类病原体鳗弧菌侵入宿主所必需的。
Mol Microbiol. 1996 Feb;19(3):625-37. doi: 10.1046/j.1365-2958.1996.412927.x.
5
Virulence studies based on plasmid profiles of the fish pathogen Vibrio salmonicida.基于鱼类病原体杀鲑气单胞菌质粒图谱的毒力研究。
Appl Environ Microbiol. 1989 Apr;55(4):819-25. doi: 10.1128/aem.55.4.819-825.1989.
6
Vibrio anguillarum Is Genetically and Phenotypically Unaffected by Long-Term Continuous Exposure to the Antibacterial Compound Tropodithietic Acid.鳗弧菌在长期持续暴露于抗菌化合物二噻吩酸的情况下，其基因和表型均未受影响。
Appl Environ Microbiol. 2016 Jul 15;82(15):4802-4810. doi: 10.1128/AEM.01047-16. Print 2016 Aug 1.
7
Development of a gene transfer system for curing of plasmids in the marine fish pathogen Vibrio salmonicida.用于消除海洋鱼类病原菌杀鲑气单胞菌中质粒的基因转移系统的开发。
Appl Environ Microbiol. 1992 Jun;58(6):1980-5. doi: 10.1128/aem.58.6.1980-1985.1992.
8
Characterization of the angR gene of Vibrio anguillarum: essential role in virulence.鳗弧菌angR基因的特性：在毒力中的重要作用
Infect Immun. 1999 Dec;67(12):6496-509. doi: 10.1128/IAI.67.12.6496-6509.1999.
9
Relationships between plasmids and phenotypes of presumptive strains of Vibrio anguillarum isolated from different fish species.从不同鱼类分离的鳗弧菌推定菌株的质粒与表型之间的关系。
Appl Environ Microbiol. 1989 Apr;55(4):826-31. doi: 10.1128/aem.55.4.826-831.1989.
10
Sequence Analysis of Plasmids in Vibrio anguillarum from Different Fish and Locations.来自不同鱼类和地点的鳗弧菌质粒的序列分析
J Aquat Anim Health. 2020 Mar;32(1):21-27. doi: 10.1002/aah.10093. Epub 2020 Jan 27.

引用本文的文献

1
Broad thermal tolerance is negatively correlated with virulence in an opportunistic bacterial pathogen.在一种机会性细菌病原体中，广泛的热耐受性与毒力呈负相关。
Evol Appl. 2018 Jul 11;11(9):1700-1714. doi: 10.1111/eva.12673. eCollection 2018 Oct.
2
Larva of the greater wax moth, Galleria mellonella, is a suitable alternative host for studying virulence of fish pathogenic Vibrio anguillarum.大蜡螟幼虫，即蜡螟绒茧蜂，是研究鱼类致病性鳗弧菌毒力的合适替代宿主。
BMC Microbiol. 2015 Jun 23;15:127. doi: 10.1186/s12866-015-0466-9.
3
Power plays: iron transport and energy transduction in pathogenic vibrios.

本文引用的文献

1
An epizootic of vibriosis in chinook salmon.奇努克鲑鱼的弧菌病流行
Wildl Dis. 1969 Apr;5(2):73-6. doi: 10.7589/0090-3558-5.2.73.
2
Properties of an R factor from Pseudomonas aeruginosa.铜绿假单胞菌R因子的特性
J Bacteriol. 1971 Dec;108(3):1244-9. doi: 10.1128/jb.108.3.1244-1249.1971.
3
Use of a single-strand specific nuclease for analysis of bacterial and plasmid deoxyribonucleic acid homo- and heteroduplexes.使用单链特异性核酸酶分析细菌和质粒脱氧核糖核酸的同源和异源双链体。
权力博弈：致病菌弧菌中的铁运输与能量转导。
Biometals. 2011 Jun;24(3):559-66. doi: 10.1007/s10534-011-9437-2. Epub 2011 Mar 12.
4
Genetic and biochemical analyses of chromosome and plasmid gene homologues encoding ICL and ArCP domains in Vibrio anguillarum strain 775.对编码鳗弧菌 775 株 ICL 和 ArCP 结构域的染色体和质粒基因同源物进行遗传和生化分析。
Biometals. 2011 Aug;24(4):629-43. doi: 10.1007/s10534-011-9416-7. Epub 2011 Feb 1.
5
Broad-host-range plasmids for red fluorescent protein labeling of gram-negative bacteria for use in the zebrafish model system.用于斑马鱼模型系统中革兰氏阴性菌红色荧光蛋白标记的广谱宿主范围质粒。
Appl Environ Microbiol. 2010 Jun;76(11):3467-74. doi: 10.1128/AEM.01679-09. Epub 2010 Apr 2.
6
Complete sequence of plasmid pMP1 from the marine environmental Vibrio vulnificus and location of its replication origin.来自海洋环境创伤弧菌的质粒pMP1的完整序列及其复制起点的定位
Mar Biotechnol (NY). 2009 Jul-Aug;11(4):456-62. doi: 10.1007/s10126-008-9160-3. Epub 2008 Nov 14.
7
Tandem heterocyclization domains in a nonribosomal peptide synthetase essential for siderophore biosynthesis in Vibrio anguillarum.鳗弧菌中铁载体生物合成所必需的非核糖体肽合成酶中的串联杂环化结构域。
Biometals. 2008 Dec;21(6):635-48. doi: 10.1007/s10534-008-9149-4. Epub 2008 Jun 13.
8
Phenotypic Characteristics and Virulence of Vibrio anguillarum-Related Organisms.鳗弧菌相关生物体的表型特征和毒力。
Appl Environ Microbiol. 1993 Sep;59(9):2969-76. doi: 10.1128/aem.59.9.2969-2976.1993.
9
Novel role of the lipopolysaccharide O1 side chain in ferric siderophore transport and virulence of Vibrio anguillarum.脂多糖O1侧链在鳗弧菌铁载体转运和毒力中的新作用
Infect Immun. 2005 Sep;73(9):5864-72. doi: 10.1128/IAI.73.9.5864-5872.2005.
10
Two tonB systems function in iron transport in Vibrio anguillarum, but only one is essential for virulence.两个tonB系统在鳗弧菌的铁转运中发挥作用，但只有一个对毒力至关重要。
Infect Immun. 2004 Dec;72(12):7326-9. doi: 10.1128/IAI.72.12.7326-7329.2004.
J Bacteriol. 1973 Sep;115(3):904-11. doi: 10.1128/jb.115.3.904-911.1973.
4
Transposition of ampicillin resistance from RP4 to other replicons.氨苄青霉素抗性从RP4转座至其他复制子。
Mol Gen Genet. 1974;132(1):31-40. doi: 10.1007/BF00268228.
5
Properties of a R factor which originated in Pseudomonas aeruginosa 1822.源自铜绿假单胞菌1822的一种R因子的特性。
J Bacteriol. 1972 May;110(2):529-37. doi: 10.1128/jb.110.2.529-537.1972.
6
Origin of the TEM-beta-lactamase gene found on plasmids.在质粒上发现的TEM-β-内酰胺酶基因的起源。
J Bacteriol. 1975 Apr;122(1):250-6. doi: 10.1128/jb.122.1.250-256.1975.
7
Failure of vaccines to protect salmon from vibriosis enzootic in Puget Sound, Washington.疫苗无法保护华盛顿普吉特海湾地区鲑鱼免受地方性弧菌病侵害。
Am J Vet Res. 1976 Jun;37(6):737-40.
8
Evidence for plasmid contribution to the virulence of fish pathogen Vibrio anguillarum.质粒对鱼类病原菌鳗弧菌毒力作用的证据。
Infect Immun. 1977 Nov;18(2):509-13. doi: 10.1128/iai.18.2.509-513.1977.
9
Deoxyribonucleic acid relationships among marine vibrios pathogenic to fish.对鱼类致病的海洋弧菌之间的脱氧核糖核酸关系。
Can J Microbiol. 1977 Aug;23(8):954-8. doi: 10.1139/m77-142.
10
Transposition of a plasmid deoxyribonucleic acid sequence that mediates ampicillin resistance: independence from host rec functions and orientation of insertion.介导氨苄青霉素抗性的质粒脱氧核糖核酸序列的转座：与宿主rec功能无关及插入方向
J Bacteriol. 1976 Oct;128(1):425-34. doi: 10.1128/jb.128.1.425-434.1976.