质粒的消除与海水鱼类病原菌鳗弧菌的毒力减弱相关。
Curing of a plasmid is correlated with an attenuation of virulence in the marine fish pathogen Vibrio anguillarum.
作者信息
Crosa J H, Hodges L L, Schiewe M H
出版信息
Infect Immun. 1980 Mar;27(3):897-902. doi: 10.1128/iai.27.3.897-902.1980.
Abstract
The transposon A sequence Tn1 containing the ampicillin resistance determinants was transposed from RP4 to a plasmid of the marine fish pathogen Vibrio anguillarum. Curing experiments in which plasmid loss was determined by analysis of the segregation of the ampicillin resistance phenotype showed the association of virulence with the specific V. anguillarum plasmid class.
摘要
携带氨苄青霉素抗性决定簇的转座子A序列Tn1从RP4转座到海洋鱼类病原菌鳗弧菌的一个质粒上。通过分析氨苄青霉素抗性表型的分离来确定质粒丢失的消除实验表明，毒力与鳗弧菌特定的质粒类别有关。
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