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Methyl group deficiency in nerve tissue: a hypothesis to explain the lesion of subacute combined degeneration.

作者信息

Dinn J J, Weir D G, McCann S, Reed B, Wilson P, Scott J M

出版信息

Ir J Med Sci. 1980 Jan;149(1):1-4. doi: 10.1007/BF02939099.

DOI:10.1007/BF02939099
PMID:6247295
Abstract
摘要

相似文献

1
Methyl group deficiency in nerve tissue: a hypothesis to explain the lesion of subacute combined degeneration.神经组织中的甲基缺乏：一种解释亚急性联合变性病变的假说。
Ir J Med Sci. 1980 Jan;149(1):1-4. doi: 10.1007/BF02939099.
2
The effect of vitamin B12 inhibition in vivo: impaired folate polyglutamate biosynthesis indicating that 5-methyltetrahydropteroylglutamate is not its usual substrate.维生素B12体内抑制作用的效果：叶酸多聚谷氨酸生物合成受损，表明5-甲基四氢蝶酰谷氨酸并非其通常的底物。
Biochem Biophys Res Commun. 1978 May 30;82(2):540-6. doi: 10.1016/0006-291x(78)90908-7.
3
Copper deficiency myelopathy and subacute combined degeneration of the cord - why is the phenotype so similar?铜缺乏性脊髓病与亚急性联合变性——为何表型如此相似？
Med Hypotheses. 2008 Aug;71(2):229-36. doi: 10.1016/j.mehy.2008.03.027. Epub 2008 May 9.
4
Effect of nitrous oxide inactivation of vitamin B12 on the levels of folate coenzymes in rat bone marrow, kidney, brain, and liver.一氧化二氮使维生素B12失活对大鼠骨髓、肾脏、大脑和肝脏中叶酸辅酶水平的影响。
Arch Biochem Biophys. 1986 Jan;244(1):248-53. doi: 10.1016/0003-9861(86)90114-1.
5
Nitrous oxide, vitamin B12 deficiency and the methyl folate trap.一氧化二氮、维生素B12缺乏与甲基叶酸陷阱
Nutr Rev. 1982 May;40(5):152-4. doi: 10.1111/j.1753-4887.1982.tb05294.x.
6
Cobalamin deficiency and the pathogenesis of nervous system disease.钴胺素缺乏与神经系统疾病的发病机制
Annu Rev Nutr. 1992;12:59-79. doi: 10.1146/annurev.nu.12.070192.000423.
7
Cobalamin-dependent methionine synthase.钴胺素依赖型甲硫氨酸合酶
FASEB J. 1990 Mar;4(5):1450-9. doi: 10.1096/fasebj.4.5.2407589.
8
Pathogenesis of subacute combined degeneration: a result of methyl group deficiency.亚急性联合变性的发病机制：甲基缺乏的结果。
Lancet. 1981 Aug 15;2(8242):334-7. doi: 10.1016/s0140-6736(81)90649-8.
9
The inhibitory effects of nitrous oxide and methylmercury in vivo on methionine synthase (EC 2.1.1.13) activity in the brain, liver, ovary and spinal cord of the rat.一氧化二氮和甲基汞在体内对大鼠脑、肝、卵巢和脊髓中蛋氨酸合成酶（EC 2.1.1.13）活性的抑制作用。
Gen Pharmacol. 1989;20(4):427-31. doi: 10.1016/0306-3623(89)90191-2.
10
Rate of inactivation of human and rodent hepatic methionine synthase by nitrous oxide.氧化亚氮对人和啮齿动物肝脏甲硫氨酸合成酶的失活速率。
Anesthesiology. 1988 Feb;68(2):213-6. doi: 10.1097/00000542-198802000-00006.

引用本文的文献

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Subacute Combined Degeneration From Isolated Folate Deficiency Secondary to Nutrition and Co-Trimoxazole Use in a Patient With IgG4-Related Disease.IgG4相关疾病患者因营养因素及使用复方新诺明继发孤立性叶酸缺乏所致的亚急性联合变性
Neurohospitalist. 2025 Sep 23:19418744251382396. doi: 10.1177/19418744251382396.
2
Neuropathy with Cerebral Features Induced by Nitrous Oxide Abuse-A Case Report.一氧化二氮滥用所致具有脑功能特征的神经病变——病例报告
Toxics. 2023 Nov 25;11(12):959. doi: 10.3390/toxics11120959.
3
Scientific opinion on the tolerable upper intake level for folate.

本文引用的文献

1
Interrelations of vitamin B12 and folic acid metabolism: folic acid clearance studies.维生素B12与叶酸代谢的相互关系：叶酸清除率研究
J Clin Invest. 1962 Jun;41(6):1263-76. doi: 10.1172/JCI104589.
2
The mechanism of coenzyme B12 action in dioldehydrase.辅酶B12在二醇脱水酶中的作用机制。
J Am Chem Soc. 1971 Mar 24;93(6):1503-5. doi: 10.1021/ja00735a039.
3
Experimental subacute combined degeneration of the cord in mice.小鼠实验性亚急性联合变性脊髓病变
关于叶酸可耐受最高摄入量的科学意见。
EFSA J. 2023 Nov 13;21(11):e08353. doi: 10.2903/j.efsa.2023.8353. eCollection 2023 Nov.
4
Role of glycine N-methyltransferase in the regulation of T-cell responses in experimental autoimmune encephalomyelitis.甘氨酸N-甲基转移酶在实验性自身免疫性脑脊髓炎中T细胞反应调节中的作用。
Mol Med. 2015 Mar 24;20(1):684-96. doi: 10.2119/molmed.2014.00133.
5
N(G)-Methylarginines: Biosynthesis, biochemical function and metabolism.N(G)-甲基精氨酸：生物合成、生化功能和代谢。
Amino Acids. 1993 Oct;4(3):267-86. doi: 10.1007/BF00805828.
6
Neurological involvement in hereditary transcobalamin II deficiency.遗传性转钴胺素II缺乏症的神经系统受累情况。
J Neurol Neurosurg Psychiatry. 1982 Jan;45(1):74-7. doi: 10.1136/jnnp.45.1.74.
7
Studies on myelin-basic-protein methylation during mouse brain development.小鼠脑发育过程中髓鞘碱性蛋白甲基化的研究。
Biochem J. 1986 Dec 1;240(2):471-9. doi: 10.1042/bj2400471.
8
Effects of methylmercury in vitro on methionine synthase activity in various rat tissues.
Bull Environ Contam Toxicol. 1990 Nov;45(5):649-54. doi: 10.1007/BF01700981.
9
Health hazards and nitrous oxide: a time for reappraisal.健康危害与一氧化二氮：重新评估的时候了。
Anesth Prog. 1991 Jan-Feb;38(1):1-11.
J Pathol. 1973 Jan;109(1):P13-14.
4
Folate deficiency and neurological disease.叶酸缺乏与神经系统疾病。
Lancet. 1965 Oct 16;2(7416):763-7. doi: 10.1016/s0140-6736(65)90813-5.
5
Folate-responsive neuropathy: report of 10 cases.叶酸反应性神经病：10例报告。
Br Med J. 1976 May 15;1(6019):1176-8. doi: 10.1136/bmj.1.6019.1176.
6
Neurological aspects of folate and vitamin B12 metabolism.
Clin Haematol. 1976 Oct;5(3):661-96.
7
Animal model for subacute combined degeneration.亚急性联合变性的动物模型。
Lancet. 1978 Nov 25;2(8100):1154. doi: 10.1016/s0140-6736(78)92314-0.
8
Selective inactivation of vitamin B12 in rats by nitrous oxide.一氧化二氮对大鼠体内维生素B12的选择性失活作用。
Lancet. 1978 Nov 11;2(8098):1023-4. doi: 10.1016/s0140-6736(78)92341-3.
9
The neurology of vitamin B12 deficiency. Metabolic mechanisms.
Lancet. 1976 Oct 16;2(7990):832-3. doi: 10.1016/s0140-6736(76)91213-7.