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[仓鼠转化细胞和肿瘤细胞的膜抗原]

[Membrane antigens of transformed and tumor cells of hamsters].

作者信息

Lavnikova N A

出版信息

Biull Eksp Biol Med. 1980 Jul;89(7):84-6.

PMID:6250657
Abstract

Normal membrane antigens to tumour and in vitro transformed tissue cultures of Syrian hamster cells were comparatively studied in cross-adsorption experiments. It was found that each cell strain has an individual profile of normal membrane antigens with characteristic quantitative and qualitative features seen on antigen expression. The absence of at least one of the antigens which the cells of other strains possessed was demonstrated with reference to the cells of each line tested. All 5 tumor cell lines were bearing antigen or a group of antigens absent on normal embryonic hamster cells (HE) and 5-strains of in vitro transformed HE cells.

摘要

在交叉吸附实验中,对叙利亚仓鼠细胞的肿瘤正常膜抗原和体外转化组织培养物进行了比较研究。发现每个细胞系都有正常膜抗原的个体特征,在抗原表达上具有特征性的定量和定性特征。参照每个测试细胞系的细胞,证实了其他细胞系所具有的至少一种抗原的缺失。所有5种肿瘤细胞系都带有正常胚胎仓鼠细胞(HE)和5种体外转化的HE细胞系所没有的抗原或一组抗原。

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