Craig E A, McCarthy B J
Nucleic Acids Res. 1980 Oct 10;8(19):4441-57. doi: 10.1093/nar/8.19.4441.
A 33 kilobase region of the 67B locus of Drosophila melanogaster genome has been isolated. The genes for the 27K, 26K, 23K and 22K heat shock induced proteins are contained within an 11 kb segment. the 27K gene, approximately 1.4 kb in length, and the 23K gene, approximately 1.0 kb in length, are separated by about 1.5 kb of spacer DNA; a third block of transcription, which encodes the 26K gene, is approximately 1.1 kb in length, and is separated from the gene for the 23K protein by 4.5 kb of spacer DNA. The 22K gene is located approximately 1.2 kb from the 26K gene. The RNAs encoding the 27K, 23K and 22K genes are transcribed from the same DNA strand. With the assignment of the four small heat shock induced proteins to 67B, genes for all seven major heat shock induced proteins have no been mapped cytologically.
果蝇黑腹基因组67B位点的一个33千碱基区域已被分离出来。27K、26K、23K和22K热休克诱导蛋白的基因包含在一个11千碱基的片段中。长度约为1.4千碱基的27K基因和长度约为1.0千碱基的23K基因被约1.5千碱基的间隔DNA隔开；编码26K基因的第三个转录单元长度约为1.1千碱基，与23K蛋白的基因被4.5千碱基的间隔DNA隔开。22K基因位于距26K基因约1.2千碱基处。编码27K、23K和22K基因的RNA从同一条DNA链转录。随着四种小热休克诱导蛋白被定位到67B，所有七种主要热休克诱导蛋白的基因尚未进行细胞学定位。
