Girshick T, Crary C K, Luginbuhl R E
Avian Dis. 1980 Apr-Jun;24(2):527-31.
A specific-pathogen-free flock of White Leghorns, which were housed conventionally and were previously serologically negative for all common poultry pathogens including avian adenoviruses, incurred an outbreak of adenovirus that was detected at about 39 weeks of age. The infection was detected serologically through the agar-gel precipitin test (AGPT) and also by a microneutralization test (MNT) adapted for 11 serotypes of avian adenovirus. The MNT detected specific antibodies to serotype-3 avian adenovirus (IBHV-Tipton) but no other serotype. While AGPT-positive sera drawn from the flock gradually declined from 54% to 17%, neutralizing-antibody levels rose sharply at 46 weeks of age to a peak that was maintained over the remaining 18 weeks of the flock's production.
一群特定病原体清除的白来航鸡，以常规方式饲养，之前对包括禽腺病毒在内的所有常见家禽病原体血清学检测均为阴性，在约39周龄时发生了腺病毒疫情。通过琼脂凝胶沉淀试验（AGPT）以及适用于11种禽腺病毒血清型的微量中和试验（MNT）进行血清学检测发现了此次感染。MNT检测到针对3型禽腺病毒（IBHV-Tipton）的特异性抗体，但未检测到其他血清型。虽然从该鸡群采集的AGPT阳性血清比例从54%逐渐降至17%，但中和抗体水平在46周龄时急剧上升至峰值，并在鸡群剩余的18周生产期内保持这一水平。
