Dixon J B, Allan D, West C R
Res Vet Sci. 1978 Jan;24(1):87-91.
Data are presented on lymphocyte transformation by phytohaemagglutinin in 20 normal horses. The logarithms of transformation ratios were found to have an approximately normal distribution, giving (for the transformation ratios themselves) a geometric mean of 23.6, a range of 1.92 to 97.3, and an estimated 95 per cent tolerance interval of 1.1 to 488. Analysis of variance on the logarithms of the transformation ratios gave a coefficient of variation of 140 per cent of the transformation ratios themselves for the variation between horses; whereas the coefficient of variation between duplicate samples was only 20 per cent, that is, small compared to the variation between horses. In addition, wide fluctuations of response of individual horses over weekly periods of measurement (comparable with the variation between the horses themselves) suggest that a single set of measurements at one time cannot be taken as evidence of abnormality in a given horse.
本文呈现了20匹正常马匹中植物血凝素诱导淋巴细胞转化的数据。发现转化比率的对数呈近似正态分布，（对于转化比率本身）几何平均数为23.6，范围为1.92至97.3，估计95%的容忍区间为1.1至488。对转化比率对数进行方差分析得出，马匹间差异导致的变异系数为转化比率本身的140%；而重复样本间的变异系数仅为20%，即与马匹间的变异相比很小。此外，在每周测量期间，个别马匹的反应波动很大（与马匹自身之间的变异相当），这表明一次测量的单一数据集不能作为某一匹马异常的证据。
