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Regulation of liver hydroxymethylglutaryl-CoA reductase by a bicyclic phosphorylation system.

作者信息

Ingebritsen T S, Parker R A, Gibson D M

出版信息

J Biol Chem. 1981 Feb 10;256(3):1138-44.

PMID:6256385
Abstract
摘要

相似文献

1
Regulation of liver hydroxymethylglutaryl-CoA reductase by a bicyclic phosphorylation system.通过双环磷酸化系统对肝脏羟甲基戊二酰辅酶A还原酶的调节。
J Biol Chem. 1981 Feb 10;256(3):1138-44.
2
Reversible modulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase: evidence for an interconvertible system.大鼠肝脏3-羟基-3-甲基戊二酰辅酶A还原酶的可逆调节：关于一个可相互转化系统的证据
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3
Phosphorylation--dephosphorylation of rat liver 3-hydroxy 3-methylglutaryl coenzyme A reductase associated with changes in activity.大鼠肝脏3-羟基-3-甲基戊二酰辅酶A还原酶的磷酸化-去磷酸化与活性变化相关。
FEBS Lett. 1980 Feb 11;110(2):195-9. doi: 10.1016/0014-5793(80)80071-8.
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Regulation of liver 3-hydroxy-3-methylglutaryl-CoA reductase.肝脏3-羟基-3-甲基戊二酰辅酶A还原酶的调节
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Reversible modulation of liver hydroxymethylglutaryl CoA reductase.
Life Sci. 1978 Dec 31;23(27-28):2649-64. doi: 10.1016/0024-3205(78)90644-6.
6
Reversible modulation of the activities of both liver microsomal hydroxymethylglutaryl coenzyme A reductase and its inactivating enzyme. Evidence for regulation by phosphorylation-dephosphorylation.肝脏微粒体羟甲基戊二酰辅酶A还原酶及其失活酶活性的可逆调节。磷酸化-去磷酸化调节的证据。
Biochem Biophys Res Commun. 1978 Apr 28;81(4):1268-77. doi: 10.1016/0006-291x(78)91273-1.
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Human hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase: evidence for the regulation of enzymic activity by a bicyclic phosphorylation cascade.人肝脏3-羟基-3-甲基戊二酰辅酶A还原酶：双环磷酸化级联对酶活性调节的证据
Biochem Biophys Res Commun. 1984 Mar 15;119(2):488-98. doi: 10.1016/s0006-291x(84)80275-2.
8
Modulation of rat liver 3-hydroxy-3-methylglutaryl-CoA reductase activity by reversible phosphorylation.可逆磷酸化对大鼠肝脏3-羟基-3-甲基戊二酰辅酶A还原酶活性的调节
Fed Proc. 1982 Aug;41(10):2634-8.
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In vivo modulation of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase, reductase kinase, and reductase kinase kinase by mevalonolactone.甲羟戊酸内酯对大鼠肝脏3-羟基-3-甲基戊二酰辅酶A还原酶、还原酶激酶及还原酶激酶激酶的体内调节作用
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3-hydroxy-3-methylglutaryl-coenzyme A reductase A comparison of the modulation in vitro by phosphorylation and dephosphorylation to modulation of enzyme activity by feeding cholesterol- or cholestryamine-supplemented diets.3-羟基-3-甲基戊二酰辅酶A还原酶：磷酸化和去磷酸化体外调节与喂食补充胆固醇或消胆胺饮食对酶活性调节的比较
Biochem J. 1980 Feb 1;185(2):435-41. doi: 10.1042/bj1850435.

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Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase.3-羟基-3-甲基戊二酰辅酶A还原酶的调节
Mol Cell Biochem. 1983;53-54(1-2):299-306. doi: 10.1007/BF00225261.
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Loss of cholesterol 7 alpha-hydroxylase activity in vitro in the presence of bivalent metal ions and by dialysis of rat liver microsomes.在二价金属离子存在的情况下以及通过对大鼠肝微粒体进行透析，体外胆固醇7α-羟化酶活性丧失。
Proc Natl Acad Sci U S A. 1983 Apr;80(8):2175-8. doi: 10.1073/pnas.80.8.2175.
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Diurnal variation in the fraction of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in the active form in the mammary gland of the lactating rat.泌乳大鼠乳腺中活性形式的3-羟基-3-甲基戊二酰辅酶A还原酶比例的昼夜变化。
Biochem J. 1986 Oct 15;239(2):285-93. doi: 10.1042/bj2390285.
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The effects of perhexiline maleate on low density lipoprotein processing and cholesterol metabolism in cultured human fibroblasts.
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Use of a selectively permeabilized isolated rat hepatocyte preparation to study changes in the properties of overt carnitine palmitoyltransferase activity in situ.使用选择性通透的分离大鼠肝细胞制剂原位研究明显的肉碱棕榈酰转移酶活性性质的变化。
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Mevalonate-metabolizing enzymes in Arachis hypogaea.花生中的甲羟戊酸代谢酶。
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Conditions that result in the mobilization and influx of Ca2+ into rat hepatocytes induce the rapid loss of 3-hydroxy-3-methylglutaryl-CoA reductase activity that is not reversed by phosphatase treatment.导致钙离子动员并流入大鼠肝细胞的情况会引发3-羟基-3-甲基戊二酰辅酶A还原酶活性迅速丧失，而这种丧失不能通过磷酸酶处理逆转。
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