Leventhal A, Pfau A
Surg Gynecol Obstet. 1978 Mar;146(3):347-8.
Postoperative bladder distention, accompanied by serious difficulties in micturition, is not a rare occurrence in surgical patients. Two similar groups of patients undergoing surgical treatment were studied. In one group of 21 patients who received phenoxybenzamine prophylactically only one patient had urinary retention develop; nine of 22 patients in the control group who did not receive prophylactic phenoxybenzamine postoperatively had urinary retention develop. All of the latter patients who then received phenoxybenzamine were ultimately relieved of voiding difficulties. Phenoxybenzamine, an alpha adrenergic blocker, is recommended as an effective and safe drug in diminishing or abolishing obstructive urinary symptoms postoperatively.
术后膀胱膨胀并伴有严重排尿困难，在外科手术患者中并不少见。我们研究了两组接受外科治疗的相似患者。在一组21例预防性使用酚苄明的患者中，只有1例发生尿潴留；而在对照组22例未接受预防性酚苄明治疗的患者中，有9例术后发生尿潴留。所有后来接受酚苄明治疗的患者最终排尿困难均得到缓解。酚苄明，一种α肾上腺素能阻滞剂，被推荐作为一种有效且安全的药物，用于减轻或消除术后梗阻性尿路症状。
