Tammela T
J Urol. 1986 Dec;136(6):1254-7. doi: 10.1016/s0022-5347(17)45304-3.
The efficacy of phenoxybenzamine and carbachol for the prevention of prolonged micturition problems was investigated in 160 consecutive patients with postoperative urinary retention. The patients were randomized into 3 groups: group 1-52 patients given 10 mg. phenoxybenzamine, group 2-55 who received 2 mg. carbachol and group 3-53 given a placebo. The drug was given orally twice daily for 3 days beginning immediately after the first catheterization. Only 17 per cent of the patients in group 1 had recurrent retention after the first catheterization compared to 49 per cent in group 2 and 57 per cent in group 3. Phenoxybenzamine is significantly more effective than carbachol or a placebo for the prevention of prolonged micturition problems in patients with unexpected urinary retention postoperatively.
对160例连续性术后尿潴留患者研究了酚苄明和卡巴胆碱预防排尿延长问题的疗效。患者被随机分为3组：第1组52例给予10 mg酚苄明，第2组55例接受2 mg卡巴胆碱，第3组53例给予安慰剂。从首次导尿后立即开始，药物每日口服2次，共3天。首次导尿后，第1组仅17%的患者出现复发性尿潴留，而第2组为49%，第3组为57%。对于预防术后意外尿潴留患者的排尿延长问题，酚苄明比卡巴胆碱或安慰剂显著更有效。
