de Leeuw P W, Ellens D J, Straver P J, van Balken J A, Moerman A, Baanvinger T
Res Vet Sci. 1980 Sep;29(2):135-41. doi: 10.1016/S0034-5288(18)32653-5.
Neonatal calf diarrhoea was studied in 115 calves of one dairy herd from January 1976 to June 1977. Two syndromes could be distinguished: a mild and short lasting 'early diarrhoea' within the first three days of life and a usually more severe 'late diarrhoea' from the fourth to the 14th day of life. The latter type of diarrhoea occurred almost exclusively during the first half of the year. Thirty-four out of 45 calves with late diarrhoea excreted rotaviruses, whereas only one of 34 calves with early diarrhoea excreted virus. In addition, rotavirus excretion was found in 11 calves that either remained healthy or had recovered from diarrhoea before virus was first detected. Similar findings were obtained in the spring of 1978 but in addition bovine coronavirus was recovered from four calves with late diarrhoea and from three healthy calves. One faecal sample obtained from a calf with diarrhoea on day 2 yielded K99+ Escherichia coli. Nearly all cows excreted rotavirus-specific antibodies in their colostrum but no relationship was found between the initial colostral antibody titre against rotavirus and the development of rotavirus-associated diarrhoea in the calf.
1976年1月至1977年6月，对一个奶牛场的115头新生犊牛的犊牛腹泻情况进行了研究。可区分出两种综合征：出生后前三天内出现的轻度且持续时间短的“早期腹泻”，以及出生后第四天至第十四天出现的通常更为严重的“晚期腹泻”。后一种腹泻类型几乎只在上半年出现。45头患有晚期腹泻的犊牛中有34头排出了轮状病毒，而34头患有早期腹泻的犊牛中只有1头排出了病毒。此外，在首次检测到病毒之前，在11头一直健康或已从腹泻中康复的犊牛中也发现了轮状病毒排出情况。1978年春季也获得了类似的结果，但此外还从4头患有晚期腹泻的犊牛和3头健康犊牛中分离出了牛冠状病毒。从一头腹泻犊牛在第2天采集的一份粪便样本中检出了K99 +大肠杆菌。几乎所有母牛的初乳中都排出了轮状病毒特异性抗体，但未发现犊牛初乳中针对轮状病毒的初始抗体滴度与轮状病毒相关腹泻的发生之间存在关联。
