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[甲型病毒性肝炎。帕多瓦及其地区的血清流行病学研究]

[Viral hepatitis type A. Seroepidemiological study in Padova and its district].

作者信息

Vendramini R, Fiaschi E, Naccarato R, Chiara-Monte M, Renzulli G, Canazza S, Trivello R

出版信息

Boll Ist Sieroter Milan. 1980 Sep 30;59(4):338-47.

PMID:6258611
Abstract

In order to ascertain the real frequency of HAV infection in North-East of Italy a seroepidemiologic survey was carried out on the population of Padova and its district. The serum samples obtained from 1812 subjects (approximately the 2% of registered people) subdivided according to sex and age (5 to 5 year groups), were tested for anti-HA by radioimmunoassay. The mean prevalence of anti-HA was 69.2%. Positive subjects' frequency of 50% was reached in 15-20 year-old group, whereas more than 90% of people over 35 years of age were positive. No significant differences were observed between the sexes or between town and country populations, while the increase of the anti-HA prevalence curve was delayed in the higher socioeconomic level group. These findings testify the relevant socioeconomic and public health levels improvement in the last decades, while, on the other hand, point out the increasing risk of adulthood HAV infection.

摘要

为了确定意大利东北部甲型肝炎病毒(HAV)感染的实际发生率,对帕多瓦及其辖区的人群进行了血清流行病学调查。从1812名受试者(约占登记人口的2%)获取血清样本,这些受试者按性别和年龄(5岁为一组)进行划分,采用放射免疫分析法检测抗-HA。抗-HA的平均流行率为69.2%。15 - 20岁年龄组的阳性受试者频率达到50%,而35岁以上人群中超过90%呈阳性。在性别之间以及城乡人群之间未观察到显著差异,而抗-HA流行率曲线的上升在社会经济水平较高的群体中有所延迟。这些发现证明了过去几十年相关社会经济和公共卫生水平的改善,另一方面也指出了成人感染HAV风险的增加。

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