Stojanović T, Djuricić B M, Mrsulja B B
Experientia. 1980 Dec 15;36(12):1348-50. doi: 10.1007/BF01960090.
The activity of (Na+ + K+)-ATPase and acetylcholine esterase were followed in rat brain cerebral cortex, caudate, thalamus, hippocampus and medulla after i.v. administration of physostigmine. Both enzymes were found to be inhibited in a dose-dependent manner. The most pronounced inhibition of (Na+ + K+)-ATPase was found in caudate, where the highest activity of acetylcholine esterase is found.
静脉注射毒扁豆碱后,对大鼠脑的大脑皮层、尾状核、丘脑、海马和延髓中(钠 + 钾)-ATP酶和乙酰胆碱酯酶的活性进行了跟踪研究。发现这两种酶均受到剂量依赖性抑制。在乙酰胆碱酯酶活性最高的尾状核中,发现(钠 + 钾)-ATP酶受到的抑制最为明显。