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3',5'-环磷酸腺苷对荚膜组织胞浆菌双态性的调控

Regulation of dimorphism in Histoplasma capsulatum by cyclic adenosine 3',5'-monophosphate.

作者信息

Medoff J, Jacobson E, Medoff G

出版信息

J Bacteriol. 1981 Mar;145(3):1452-5. doi: 10.1128/jb.145.3.1452-1455.1981.

DOI:10.1128/jb.145.3.1452-1455.1981
PMID:6259135
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC217157/
Abstract

During temperature-induced transition of the dimorphic pathogenic fungus Histoplasma capsulatum from the single yeast cell form to the multicellular mycelial form, there was an increase in intracellular cyclic adenosine 3',5'-monophosphate (cAMP) levels as well as a striking accumulation of cAMP in the medium. cAMP levels also changed during the reverse mycelium-to-yeast transition.

摘要

在温度诱导下，双态致病真菌荚膜组织胞浆菌从单一酵母细胞形态转变为多细胞菌丝形态的过程中，细胞内3',5'-环磷酸腺苷（cAMP）水平升高，同时培养基中cAMP显著积累。在菌丝向酵母的反向转变过程中，cAMP水平也发生了变化。

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本文引用的文献

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Studies on the dimorphism of Histoplasma capsulatum. I. The roles of -SH groups and incubation temperature.荚膜组织胞浆菌二态性的研究。I. -SH基团和培养温度的作用。
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Regulation of dimorphism in the pathogenic fungus Histoplasma capsulatum.荚膜组织胞浆菌致病性真菌中双态性的调控。
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