在其他药理学试验中为激动剂的苯并吗啡烷类药物在大鼠输精管中出现意外的拮抗作用。
Unexpected antagonism in the rat vas deferens by benzomorphans which are agonists in other pharmacological tests.
作者信息
Gillan M G, Kosterlitz H W, Magnan J
出版信息
Br J Pharmacol. 1981 Jan;72(1):13-5. doi: 10.1111/j.1476-5381.1981.tb09098.x.
Abstract
The benzomorphans, ethylketazocine, bremazocine and MR 2034 are pure agonists in the guinea-pig ileum and mouse vas deferens but are competitive antagonists without agonist activity in the rat vas deferens.
摘要
苯并吗啡烷类、乙基酮佐辛、布马佐辛和MR 2034在豚鼠回肠和小鼠输精管中是纯激动剂，但在大鼠输精管中是没有激动剂活性的竞争性拮抗剂。
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