豚鼠唇部环核苷酸的免疫组织化学定位
Immunohistochemical localization of cyclic nucleotides in guinea pig lip.
作者信息
Miyachi Y, Imamura S, Tanaka C, Kuno T, Yoshida N
出版信息
Arch Dermatol Res. 1980;269(3):233-7. doi: 10.1007/BF00406416.
PMID:6263191
Abstract
The cellular localization of cAMP and cGMP in the guinea pig lip was investigated with an indirect immunofluorescence technique. cAMP was distributed both in cell membranes and cytoplasmic elements with coarse and granular intranuclear fluorescence, while cGMP was localized in nuclear sites including nuclear membranes as well as cell membranes and cytoplasm. In the basal portion, both cAMP and cGMP fluorescence was weaker in cytoplasm and cell membranes than seen in the upper portion.
摘要
采用间接免疫荧光技术研究了环磷酸腺苷（cAMP）和环磷酸鸟苷（cGMP）在豚鼠唇部的细胞定位。cAMP分布于细胞膜和细胞质成分中，核内有粗大颗粒状荧光，而cGMP定位于包括核膜以及细胞膜和细胞质在内的核部位。在基部，cAMP和cGMP在细胞质和细胞膜中的荧光比在上部弱。
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