Pelosi G, Campari M, Ferrari C
Ateneo Parmense Acta Biomed. 1980;51(6):521-30.
The most recent data concerning the characteristics of hepatitis A virus, as well as epidemiology and prophylaxis of type A hepatitis are described. An epidemic of hepatitis A which occurred in a village near Parma is analysed. The diagnosis was based on the detection, by radioimmunoassay, of specific antibody to hepatitis A antigen (anti-HAV) at the beginning of the infection and during the convalescence. In addition the occurrence of high levels of specific immunoglobulins type M anti HAV, during the acute phase, was a further evidence of the diagnosis. The presence of other agents responsible for acute hepatitis, such as Cytomegalovirus and Epstein-Barr virus, has been excluded by laboratory examination.
本文描述了有关甲型肝炎病毒特征、甲型肝炎流行病学及预防的最新数据。分析了帕尔马附近一个村庄发生的甲型肝炎疫情。诊断依据是在感染初期及恢复期通过放射免疫测定法检测甲型肝炎抗原特异性抗体（抗-HAV）。此外，急性期特异性免疫球蛋白M抗-HAV水平升高也是诊断的进一步证据。通过实验室检查排除了其他导致急性肝炎的病原体，如巨细胞病毒和爱泼斯坦-巴尔病毒。
