The blockade of Vmax of the atrioventricular action potential produced by the slow channel inhibitors verapamil and nifedipine.

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作者信息

Kohlhardt M, Haap K

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1981 Apr;316(2):178-85. doi: 10.1007/BF00505314.

DOI:10.1007/BF00505314

PMID:6264331

Abstract

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The blockade of Vmax of the atrioventricular action potential produced by the slow channel inhibitors verapamil and nifedipine.

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Comparison of the direct effects of nifedipine and verapamil on the electrical activity of the sinoatrial and atrioventricular nodes of the rabbit heart.硝苯地平与维拉帕米对兔心脏窦房结和房室结电活动直接影响的比较。

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本文引用的文献

Electrical activity of single fibers of the atrioventricular node.房室结单纤维的电活动。

Circ Res. 1959 Jan;7(1):11-8. doi: 10.1161/01.res.7.1.11.

Transmembrane potentials of single fibres of the atrio-ventricular node.

Nature. 1958 Jan 4;181(4601):66-7. doi: 10.1038/181066a0.

Slow current systems in the A-V node of the rabbit heart.

Nature. 1980 May 22;285(5762):228-9. doi: 10.1038/285228a0.

Two components of the cardiac action potential. I. Voltage-time course and the effect of acetylcholine on atrial and nodal cells of the rabbit heart.心脏动作电位的两个组成部分。I. 电压-时间过程以及乙酰胆碱对兔心脏心房和节点细胞的影响。

J Gen Physiol. 1969 Nov;54(5):607-35. doi: 10.1085/jgp.54.5.607.

Action of manganese ions and tetrodotoxin on atrioventricular nodal transmembrane potentials in isolated rabbit hearts.

Circ Res. 1973 Apr;32(4):447-54. doi: 10.1161/01.res.32.4.447.

Differentiation of the transmembrane Na and Ca channels in mammalian cardiac fibres by the use of specific inhibitors.利用特异性抑制剂对哺乳动物心脏纤维中跨膜钠通道和钙通道进行区分。

Pflugers Arch. 1972;335(4):309-22. doi: 10.1007/BF00586221.

The effect of polarization on the action potentials of the rabbit AV nodal cells.极化对家兔房室结细胞动作电位的影响。

Jpn J Physiol. 1974 Dec;24(6):605-16. doi: 10.2170/jjphysiol.24.605.

Effect of verapamil on the sinoatrial and atrioventricular nodes of the rabbit and the mechanism by which it arrests reentrant atrioventricular nodal tachycardia.维拉帕米对兔窦房结和房室结的作用及其终止折返性房室结性心动过速的机制。

Circ Res. 1974 Sep;35(3):413-25. doi: 10.1161/01.res.35.3.413.

The interrelationship of calcium-mediated action potentials and tension development in cat ventricular myocardium.

J Mol Cell Cardiol. 1976 Apr;8(4):249-61. doi: 10.1016/0022-2828(76)90001-8.

The slow membrane channel as the predominant mediator of the excitation process of the sinoatrial pacemaker cell.

Basic Res Cardiol. 1976 Jan-Feb;71(1):17-26. doi: 10.1007/BF01907779.

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