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[维尔恰地区慢性肺结核病例的治疗模型]

[Model for the treatment of cases of chronic pulmonary tuberculosis in the Vîlcea district].

作者信息

Mihăilescu P, Mardale C, Alexandridis V, Cristina C, Cîţu M, Călugăru A, Pufu L

出版信息

Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol. 1981 Apr-Jun;30(2):79-84.

PMID:6264580
Abstract

Patients with pulmonary tuberculosis are considered to be chronic cases when they continue to eliminate bacilli after one year after registration and start of treatment. The chronic cases are classified in the I B dispensary group. Following the introduction of the chemotherapy program the number of chronic patients with tuberculosis has dropped appreciably after 1974. However the rate of decrease has diminished between 1978 and 1979. In view of evaluating the possibilities for recuperation of chronic patients a research was organized in several districts. In one of them, the Vilcea District, it was noted that in spite of the fact that each year a large number of patients from group IB are eliminated, either following negativation of their sputum examinations, or by death, the total number of patients in the group itself does not decrease, since it is continuously fueled by failures of the initial treatments, and by relapses in the first two years after the end of the treatment. The analysis of the chronic cases in evidence on the 1-st of January 1980 showed that there are possibilities for recuperation by chemotherapy in 44,8% of the patients, and by surgery in another 9,5%. Only 23,8% are considered as non-recuperable. The authors review the technical and organizational measures which are indicated in view of solving the existing cases, and for the prevention of other chronicization. The short-term prognosis indicates the possibility for reducing the prevalence of chronic patients by more than 50% over a period of 3 years.

摘要

肺结核患者在登记并开始治疗一年后仍持续排菌的,被视为慢性病例。这些慢性病例被归类于IB诊疗组。自化疗方案实施后,1974年以后肺结核慢性病患者数量显著下降。然而,1978年至1979年期间下降速度有所减缓。为评估慢性病患者康复的可能性,在几个地区组织了一项研究。其中一个地区是维尔恰县,研究发现,尽管每年有大量来自IB组的患者因痰检转阴或死亡而被剔除,但该组患者总数并未减少,因为初始治疗失败以及治疗结束后头两年的复发不断补充着该组患者数量。对1980年1月1日现有慢性病病例的分析表明,44.8%的患者有可能通过化疗康复,另有9.5%的患者可通过手术康复。只有23.8%的患者被认为无法康复。作者回顾了为解决现有病例及预防其他慢性化情况而需采取的技术和组织措施。短期预后显示,在3年时间里将慢性病患者患病率降低50%以上是有可能的。

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