Balázs M
Exp Pathol. 1981;19(3):164-71. doi: 10.1016/s0232-1513(81)80060-6.
The electron-microscopic characteristics of the LEUCHTENBERGER'S inclusion bodies were studied in adenomatous, papillary and adeno-papillary polyps of the colon. According to them, formation of intracellular inclusions is due to focal cytoplasmic degradation, and that of intercellular inclusions to the herniation of the cytoplasmic part of epithelial cells. The formation of inclusions is believed to be connected with the low stage of development of the plasma membrane of rapidly proliferating undifferentiated colonic epithelial cells. During malignant transformation of polyps, the frequently occurring inclusions are considered an important morphological sign.
在结肠的腺瘤性、乳头状和腺乳头状息肉中研究了洛伊滕贝格包涵体的电子显微镜特征。据此，细胞内包涵体的形成是由于局部细胞质降解，而细胞间包涵体的形成是由于上皮细胞细胞质部分的疝出。包涵体的形成被认为与快速增殖的未分化结肠上皮细胞质膜发育的低阶段有关。在息肉的恶性转化过程中，频繁出现的包涵体被认为是一个重要的形态学标志。
