对5岁以下囊性纤维化患儿进行的系列肺功能研究。
Serial lung function studies in cystic fibrosis in the first 5 years of life.
作者信息
Godfrey S, Mearns M, Howlett G
出版信息
Arch Dis Child. 1978 Jan;53(1):83-5. doi: 10.1136/adc.53.1.83.
Abstract
Lung mechanics were studied in 8 infants with cystic fibrosis at 6 months of life and radiosotopic lung function was measured in 5 of them at 5 years of age. The children who were initially asymptomatic had normal lung mechanics in infancy but the 2 restudied later had abnormal radioisotopic lung function. The symptomatic children showed abnormalities in infancy and more marked changes later. It is concluded that the lungs in cystic fibrosis are probably normal initially and that damage occurs later even in the absence of symptoms.
摘要
对8名6个月大的囊性纤维化婴儿进行了肺力学研究，并对其中5名5岁儿童进行了放射性同位素肺功能测量。最初无症状的儿童在婴儿期肺力学正常，但后来再次研究的2名儿童放射性同位素肺功能异常。有症状的儿童在婴儿期就出现异常，后期变化更明显。得出的结论是，囊性纤维化患者的肺部最初可能是正常的，即使没有症状，后期也会发生损伤。
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