Bergh N P, Gatzinsky P, Larsson S, Lundin P, Ridell B
Ann Thorac Surg. 1978 Feb;25(2):99-106. doi: 10.1016/s0003-4975(10)63499-6.
Among 82 patients with a tumor in the thymic region, 17 had a lesion that fulfilled the criteria for Hodgkin's disease of the thymus; the histopathological differentiation of this entity from thymomas is discussed. All patients received surgical treatment and postoperative radiotherapy. After a mean observation time of 10 years there was no local recurrence and no death due to the disease, though 3 deaths were cuased by the treatment. New clinical manifestations occurred in 3 of the 14 long-term survivors: they were treated successfully by operation or irradiation. A very aggressive surgical approach involving extirpation of all tumor tissue, extensive excision of the surrounding tissues and adjacent lymph nodes, and supplementary radiotherapy seems to be the treatment of choice.
在82例胸腺区域有肿瘤的患者中，17例有符合胸腺霍奇金病标准的病变；讨论了该实体与胸腺瘤的组织病理学鉴别。所有患者均接受了手术治疗和术后放疗。平均观察10年后，无局部复发，也无因该病死亡者，不过有3例死亡是由治疗引起的。14例长期存活者中有3例出现了新的临床表现：经手术或放疗成功治疗。一种非常积极的手术方法，包括切除所有肿瘤组织、广泛切除周围组织和相邻淋巴结，并辅以放疗，似乎是首选的治疗方法。
