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慢性给予锂对甲状腺毒症患者甲状腺素(T4)、三碘甲状腺原氨酸(T3)、反三碘甲状腺原氨酸(rT3)、游离甲状腺素比值(FTR)及促甲状腺素(TSH)的影响(作者译)

[Effects of chronic administration of lithium on thyroxine (T4), triiodothyronine (T3), reverse T3 (rT3) free thyroxine ratio (FTR) and thyreostimuline (TSH) in thyrotoxicosis (author's transl)].

作者信息

Heim J, Lorcy Y, Auvray E, Ricolleau G, Allannic H

出版信息

Sem Hop. 1981;57(25-28):1202-5.

PMID:6266038
Abstract

Fourteen hyperthyroid subjects were studied between 3 and 141 days. The reduction of thyrotoxicosis is rarely obtained (2 cases), mainly because on the one hand, correct plasma lithium level (0.7-1.2 mEq/L) is rarely obtained (3 cases only), on the other hand because a high dose of lithium is required, perhaps owing to high clearance of lithium in thyrotoxicosis. The indications of lithium use in thyrotoxicosis are reviewed.

摘要

对14名甲状腺功能亢进患者进行了3至141天的研究。很少能实现甲状腺毒症的减轻(仅2例),主要原因一方面是很少能达到正确的血浆锂水平(0.7 - 1.2毫当量/升)(仅3例),另一方面是由于甲状腺毒症时锂清除率高,可能需要高剂量的锂。本文对锂在甲状腺毒症中的应用指征进行了综述。

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