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低三碘甲状腺原氨酸及高三碘甲状腺原氨酸逆浓度血症所致甲状腺毒症。9例(作者译)

[Thyrotoxicosis with low T3 and high reverse T3 levels. 9 cases (author's transl)].

作者信息

Schlienger J L, Chabrier G, Stephan F, Sapin R

出版信息

Nouv Presse Med. 1980 Jan 5;9(1):30.

PMID:7355063
Abstract

In common forms of hyperthyroidism serum levels of triiodothyronin (T3) are higher than those of thyroxin (T4) and isolated elevations of serum T3 have even been noted. We report 9 cases of proven hyperthyroidism with normal or low levels of T3 and elevated T4 and reverse T3 (rT3). Most out of the patients were more than seventy years old and had associated diseases. Our data show that the low T3 with elevated rT3 syndrome--which has been noted in many metabolic and pathologic conditions--can coexist in hyperthyroidism. They emphasize the lack of diagnostic discrimination of T3 assays in thyroid dysfunction especially in the older patient or one with associated disease.

摘要

在常见类型的甲状腺功能亢进症中,血清三碘甲状腺原氨酸(T3)水平高于甲状腺素(T4),甚至有血清T3单独升高的情况。我们报告了9例经证实的甲状腺功能亢进症患者,其T3水平正常或降低,而T4和反T3(rT3)升高。大多数患者年龄超过70岁且伴有其他疾病。我们的数据表明,在许多代谢和病理状况中都有记录的低T3伴rT3升高综合征可与甲状腺功能亢进症并存。这些数据强调了T3检测在甲状腺功能障碍诊断中的鉴别能力不足,尤其是在老年患者或伴有其他疾病的患者中。

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