Coohill T P, Babich M, Taylor W D, Snipes W
Biophys J. 1980 Jun;30(3):517-21. doi: 10.1016/S0006-3495(80)85111-3.
The plaque development of Herpes simplex virus type 1 (HSV) is slower for viruses treated with two anti-DNA agents: ultraviolet radiation (UV) or n-acetoxy-2-acetyl-aminofluorene. For HSV treated with three antimembrane agents--butylated hydroxytoluene, acridine plus near UV radiation, or ether--the plaque development time is the same as for untreated viruses. These differences hold even for viruses that survived treatment that lowered viability below the 1% level. Gamma ray inactivation of HSV produces no change in plaque development even though this agent is believed to preferentially affect viral DNA.
对于用两种抗DNA药物（紫外线辐射（UV）或N-乙酰氧基-2-乙酰氨基芴）处理的1型单纯疱疹病毒（HSV），其蚀斑形成较慢。对于用三种抗膜药物（丁基化羟基甲苯、吖啶加近紫外线辐射或乙醚）处理的HSV，蚀斑形成时间与未处理的病毒相同。即使对于那些在处理后存活率降至1%以下仍存活的病毒，这些差异依然存在。HSV经伽马射线灭活后蚀斑形成没有变化，尽管据信这种药物会优先影响病毒DNA。
