Pavlou C, Barker G H, Roberts A, Chamberlain G V
Br J Obstet Gynaecol. 1978 Feb;85(2):96-100. doi: 10.1111/j.1471-0528.1978.tb10460.x.
A randomized controlled trial was mounted in which induction of labour at term was successfully accomplished in 12 patients by amniotomy and intermittent (or pulsed) oxytocin, compared with 16 patients receiving continuous oxytocin. In the pulsed group, oxytocin was infused for one minute in every ten using a modified Cardiff Infusion System Mark III in the automatic setting. Compared with the control group the induction-delivery and induction-to-full-dilatation intervals were similar but the total dose of oxytocin required was significantly lower in the pulsed group than in the control group.
开展了一项随机对照试验,其中12例患者通过人工破膜和间歇性(或脉冲式)缩宫素成功实现足月引产,与之相比,16例患者接受持续性缩宫素治疗。在脉冲组中,使用改良的卡迪夫输注系统Mark III自动设置,每十分钟输注缩宫素一分钟。与对照组相比,引产至分娩和引产至宫口开全的间隔时间相似,但脉冲组所需缩宫素的总剂量显著低于对照组。