Neild T O
Brain Res. 1978 Jan 27;140(2):231-9. doi: 10.1016/0006-8993(78)90457-2.
Intracellular recordings were made from cells of the isolated guinea-pig inferior mesenteric ganglion. Stimulation of both hypogastric nerves at 30 Hz for 2 sec caused a slowly developing depolarization (SD) and fall in cell input resistance which reached a peak 10-30 sec after the end of stimulation. The amplitude of the SD was increased in a graded manner if the stimulus voltage was increased. The SD was unaffected by tubocurarine, atropine or guanethidine, but was blocked by removing external Ca. These results suggested that the SD was caused by the release of some substance from a large number of nerve terminals.
从分离的豚鼠肠系膜下神经节细胞进行细胞内记录。以30Hz的频率刺激双侧腹下神经2秒，会引起缓慢发展的去极化（SD）以及细胞输入电阻下降，在刺激结束后10 - 30秒达到峰值。如果刺激电压增加，SD的幅度会以分级的方式增加。SD不受筒箭毒碱、阿托品或胍乙啶的影响，但通过去除细胞外钙而被阻断。这些结果表明，SD是由大量神经末梢释放某种物质所引起的。
