Benjamin R M, Jackson J C, Golden G T
Brain Res. 1978 Feb 10;141(2):251-65. doi: 10.1016/0006-8993(78)90196-8.
The cortical projection of the thalamic mediodorsal nuclear complex (MD) in the rabbit was mapped retrograde horseradish peroxidase and anterograde tritiated proline techniques. The projection field occupied the entire medial wall rostral to a mid corpus callosal level, wrapped around the frontal pole onto the lateral convexity and tailed off caudally on the dorsal bank of the rhinal sulcus. The projection of the lateral approximately one-half of MD, the half which does not receive olfactory input, was confined to medial cortex supply all but the most rostral region. This projection field of lateral MD was precisely organized in two dimensions with the most lateral part projecting most caudally and the most dorsal part projecting most ventrally. A representation for the third, anterior-posterior (A-P), dimension was not evident since any cortical point within the field was supplied by a cylinder of cells extending the entire A-P extent of lateral MD. The medial half of MD, which does receive olfactory input, projected to the remaining rostral medical cortex, the lateral convexity and rhinal sulcal region. The inverse dorsoventral relationship was partially preserved and on overlapping A-P gradient was present with sulcal projections originating more caudally in medial MD and the rostral medial projection originating more rostrally.
采用逆行辣根过氧化物酶和顺行氚化脯氨酸技术绘制了家兔丘脑内侧背核复合体（MD）的皮质投射图。投射区域占据胼胝体中部水平前方的整个内侧壁，围绕额极延伸至外侧凸面，并在鼻沟背侧缘尾部逐渐变细。MD外侧大约一半的投射，即不接受嗅觉输入的那一半，局限于内侧皮质，供应除最前端区域之外的所有区域。外侧MD的这个投射区域在二维上精确组织，最外侧部分投射到最尾端，最背侧部分投射到最腹侧。第三维度，即前后（A-P）维度的表征并不明显，因为该区域内的任何皮质点都由延伸至外侧MD整个A-P范围的细胞柱供应。接受嗅觉输入的MD内侧一半投射到其余的前端内侧皮质、外侧凸面和鼻沟区域。背腹关系的倒置部分保留，并且存在重叠的A-P梯度，鼻沟投射起源于内侧MD更靠尾端的部位，而前端内侧投射起源于更靠前的部位。
