Papadopoulos N M
Clin Chem. 1978 Feb;24(2):227-9.
Hyperlipoproteinemia phenotyping has been re-evaluated by an improved agarose gel electrophoretic test. Eight varieties of serum lipoprotein electrophoretic patterns are demonstrated, two from clinically normal normolipidemic subjects and six from patients with hyperlipoproteinemia that include the phenotypes 1, 2a, 2b, 3, 4, and 5. The sharp delineation of the lipoprotein patterns achieved by this technique facilitates the differentiation and identifcation of the lipoprotein phenotypes. Furthermore, the lipoprotein patterns can be visually evaluated, correlated with their corresponding serum lipid values, and associated with the clinical and hereditary features of the hyperlipoproteinemia phenotypes. This test system can also be used in clinical trials and epidemiological studies.
通过改进的琼脂糖凝胶电泳试验对高脂蛋白血症表型进行了重新评估。展示了八种血清脂蛋白电泳模式，两种来自临床正常的血脂正常受试者，六种来自高脂蛋白血症患者，包括表型1、2a、2b、3、4和5。通过该技术实现的脂蛋白模式的清晰描绘有助于脂蛋白表型的鉴别和识别。此外，脂蛋白模式可以直观评估，与相应的血清脂质值相关，并与高脂蛋白血症表型的临床和遗传特征相关联。该测试系统也可用于临床试验和流行病学研究。
