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大鼠新纹状体中两种多巴胺能神经终末:一项超微结构研究

Two types of dopaminergic nerve terminals in the rat neostriatum. An ultrastructural study.

作者信息

Kaiya H, Namba M

出版信息

Neurosci Lett. 1981 Sep 25;25(3):251-6. doi: 10.1016/0304-3940(81)90400-6.

DOI:10.1016/0304-3940(81)90400-6
PMID:6270601
Abstract

In the neostriatum 7.7% of all boutons absorbed alpha-methylnoradrenaline, thus staining their synaptic vesicles profiles granular. These presumably monoaminergic synapses were divided into two types according to ultrastructural features. Type A was composed of a relatively large axon terminal and a dendritic spine with postsynaptic membrane thickening. The axon terminal of type B, that is a bouton en passant, was smaller than the postsynaptic profile, while the synaptic contact was symmetrical. Following nigral coagulation, both types of synapse degenerated. It is concluded that both types of synapse are dopaminergic.

摘要

在新纹状体中,所有终扣中有7.7%摄取了α-甲基去甲肾上腺素,从而使它们的突触小泡轮廓呈现颗粒状染色。这些推测为单胺能的突触根据超微结构特征分为两种类型。A型由一个相对较大的轴突终末和一个具有突触后膜增厚的树突棘组成。B型轴突终末即一个旁过终扣,比突触后结构小,而突触接触是对称的。黑质凝固后,两种类型的突触都发生退变。结论是这两种类型的突触都是多巴胺能的。

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