Carfagnini J C, Rehbinder C, Rönnbäck C
Acta Radiol Oncol. 1981;20(3):199-208. doi: 10.3109/02841868109130196.
The radiation protective action of 2,2'-Dithiobis(N-[(1-adamantyl)-methyl]-acetamidine)-dihyrochloride (S-75) and cysteamine was compared in splenectomized and non-splenectomized mice. Cysteamine was found to have better and more general protection properties. Several indications of a specific effect of S-75 on the spleen were observed. It is suggested that the protection properties of S-75 should be tested in another laboratory animal not having such a marked splenic haemopoiesis as the mouse.
在脾切除和未脾切除的小鼠中比较了2,2'-二硫代双（N-[(1-金刚烷基)-甲基]-乙脒）二盐酸盐（S-75）和半胱胺的辐射防护作用。发现半胱胺具有更好且更普遍的防护特性。观察到了S-75对脾脏有特定作用的若干迹象。建议在另一种不像小鼠那样具有如此显著脾造血功能的实验动物中测试S-75的防护特性。
