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完整人体肌肉的糖酵解与氧化能量代谢及收缩特性

Glycolytic and oxidative energy metabolism and contraction characteristics of intact human muscle.

作者信息

Hultman E, Sjöholm H, Sahlin K, Edström L

出版信息

Ciba Found Symp. 1981;82:19-40.

PMID:6271506
Abstract

It is proposed that glycolytic rate may be measured as lactate accumulation after electrical stimulation of the quadriceps femoris muscle under anaerobic conditions. The ratio of glucose 6-phosphate to lactate is an internal monitor of the glycolytic pathway. The phosphocreatine/lactate ratio links glycolysis and the creatine kinase reaction and could be used to distinguish abnormalities in energy metabolism. The rate of resynthesis of phosphocreatine after stimulation when the circulation is restored should be measure of oxidative phosphorylation. The relaxation rate seems to be a mechanical index of the metabolic state of the muscle.

摘要

有人提出,在无氧条件下对股四头肌进行电刺激后,糖酵解速率可通过乳酸积累来测量。6-磷酸葡萄糖与乳酸的比值是糖酵解途径的一种内部监测指标。磷酸肌酸/乳酸比值将糖酵解和肌酸激酶反应联系起来,可用于区分能量代谢异常。恢复循环后刺激时磷酸肌酸的重新合成速率应是氧化磷酸化的一个指标。松弛速率似乎是肌肉代谢状态的一个机械指标。

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