水痘-带状疱疹免疫球蛋白的制备。

Preparation of varicella-herpes zoster immunoglobulin.

作者信息

Janot C, Stoltz J F, Avenard G, Perrier P, Schooneman F, Streiff F

出版信息

Transfusion. 1981 Nov-Dec;21(6):732-4. doi: 10.1046/j.1537-2995.1981.21682085765.x.

DOI:10.1046/j.1537-2995.1981.21682085765.x

Abstract

The efficacy of zoster immunoglobulin in prophylaxis of varicella and herpes zoster is reported by many authors. The screening for zoster's antibodies is performed in the blood donor population and in persons convalescing from herpes zoster. The results show that 25 per cent of blood donors and 83.5 per cent of convalescents, respectively, have CF antibody titer of l6. Varicella zoster immunoglobulin prepared by alcohol fractionation has a fluorescent antibody titer of 1,024 and a CF antibody titer of 512. These results are discussed and compared with those of the literature.

摘要

许多作者报告了带状疱疹免疫球蛋白在预防水痘和带状疱疹方面的疗效。在献血人群和带状疱疹康复者中进行了带状疱疹抗体筛查。结果显示，献血者和康复者中分别有25%和83.5%的人补体结合（CF）抗体效价为16。通过酒精分级分离制备的水痘带状疱疹免疫球蛋白荧光抗体效价为1024，补体结合抗体效价为512。对这些结果进行了讨论并与文献中的结果进行了比较。