[抗水痘带状疱疹免疫球蛋白。抗体的发现及形成方法]

[Anti-varicella-zona immunoglobulins. Discovery of antibodies and method of formation].

作者信息

Janot C, Perrier P, Schooneman F, Streiff F, Stoltz J F, Avenard G, Amouch J P

出版信息

Rev Fr Transfus Immunohematol. 1980 Sep;23(4):439-48. doi: 10.1016/s0338-4535(80)80169-3.

Abstract

The screening of zoster's antibodies has been performed in blood donors population and persons convalescing from herpes zoster. The results show that 25% of blood donors and 83,5% of convalescents have respectively a titer of CF antibody of 8. Plasma units were pooled and the pool had a final titer of CF antibody of 16. Varicella zoster immunoglobulin prepared by alcohol fractionation had a fluorescent antibody titer of 1 024 and a CF antibody of 512. These results are discussed and compared with those of literature.

摘要

已对献血人群和带状疱疹康复者进行了带状疱疹抗体筛查。结果显示，25%的献血者和83.5%的康复者CF抗体滴度分别为8。将血浆单位合并后，合并血浆的CF抗体最终滴度为16。通过乙醇分级分离制备的水痘带状疱疹免疫球蛋白荧光抗体滴度为1024，CF抗体滴度为512。对这些结果进行了讨论并与文献结果进行了比较。