灌注兔肝脏中对IgG和IgM包被的绵羊红细胞的摄取。
The uptake of IgG and IgM coated sheep erythrocytes in perfused rabbit liver.
作者信息
Hällgren R, Sjöström P, Bill A
出版信息
Immunology. 1978 Feb;34(2):347-51.
Abstract
Erythrocytes sensitized with IgM and IgG (EA) are entrapped during perfusion of isolated rabbit liver. The binding of EIgG is of high affinity while that of EIgM is weak and partly reversible. Moreover, the binding of EIgM is dependent on the presence of Ca++ ions in the perfusion medium whilst the binding of EIgG is independent of divalent cations. No uptake of sensitized erythrocytes during perfusion of the inferior extremities of rabbits is found.
摘要
用IgM和IgG致敏的红细胞（EA）在离体兔肝灌注过程中被截留。EIgG的结合具有高亲和力，而EIgM的结合较弱且部分可逆。此外，EIgM的结合依赖于灌注介质中Ca++离子的存在，而EIgG的结合不依赖于二价阳离子。在兔下肢灌注过程中未发现致敏红细胞的摄取。
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