用75Se-硒代叶酸放射分析法测定红细胞叶酸
Measurement of red cell folate with 75Se-selenofolate radioassay.
作者信息
Johnson I, Rose M
出版信息
J Clin Pathol. 1978 Jan;31(1):47-9. doi: 10.1136/jcp.31.1.47.
Abstract
75Se-selenofolate radioassay was adapted for the purpose of red cell folate measurement. The results of assay of 124 whole blood samples by Lactobacillus casei microbiological assay and by radioassay using the adapted selenofolate method were concordant (r = 0.8). Red cell folate levels by the radioassay were below 170 microgram/1 in people who had haematological features of folate depletion. The distribution of results among reputedly healthy subjects extended down to 140 microgram/1.
摘要
为了测量红细胞叶酸，采用了75Se-硒代叶酸放射分析法。用干酪乳杆菌微生物分析法和采用改良硒代叶酸法的放射分析法对124份全血样本进行检测，结果具有一致性（r = 0.8）。采用放射分析法时，有叶酸缺乏血液学特征的人群红细胞叶酸水平低于170微克/升。在据称健康的受试者中，检测结果分布低至140微克/升。
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