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Gene amplification in methotrexate-resistant mouse cells. II. Rearrangement and amplification of non-dihydrofolate reductase gene sequences accompany chromosomal changes.

作者信息

Bostock C J, Tyler-Smith C

出版信息

J Mol Biol. 1981 Dec 5;153(2):219-36. doi: 10.1016/0022-2836(81)90275-8.

DOI:10.1016/0022-2836(81)90275-8
PMID:6279871
Abstract
摘要

相似文献

1
Gene amplification in methotrexate-resistant mouse cells. II. Rearrangement and amplification of non-dihydrofolate reductase gene sequences accompany chromosomal changes.甲氨蝶呤抗性小鼠细胞中的基因扩增。II. 非二氢叶酸还原酶基因序列的重排和扩增伴随染色体变化。
J Mol Biol. 1981 Dec 5;153(2):219-36. doi: 10.1016/0022-2836(81)90275-8.
2
Gene amplification in methotrexate-resistant mouse cells. I. DNA rearrangement accompanies dihydrofolate reductase gene amplification in a T-cell lymphoma.甲氨蝶呤抗性小鼠细胞中的基因扩增。I. DNA重排伴随T细胞淋巴瘤中二氢叶酸还原酶基因扩增。
J Mol Biol. 1981 Dec 5;153(2):203-18. doi: 10.1016/0022-2836(81)90274-6.
3
Gene amplification in methotrexate-resistant mouse cells. III. Interrelationships between chromosome changes and DNA sequence amplification or loss.
J Mol Biol. 1981 Dec 5;153(2):237-56. doi: 10.1016/0022-2836(81)90276-x.
4
Increased gene amplification in L5178Y mouse lymphoma cells with hydroxyurea-induced chromosomal aberrations.羟基脲诱导染色体畸变的L5178Y小鼠淋巴瘤细胞中基因扩增增加。
Cancer Res. 1985 Oct;45(10):5050-7.
5
Relationship of amplified dihydrofolate reductase genes to double minute chromosomes in unstably resistant mouse fibroblast cell lines.不稳定抗性小鼠成纤维细胞系中扩增的二氢叶酸还原酶基因与双微体染色体的关系。
Mol Cell Biol. 1981 Dec;1(12):1077-83. doi: 10.1128/mcb.1.12.1077-1083.1981.
6
Gene amplification in methotrexate-resistant mouse cells. IV. Different DNA sequences are amplified in different resistant lines.
Nucleic Acids Res. 1982 Nov 11;10(21):6597-618. doi: 10.1093/nar/10.21.6597.
7
Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes.在不稳定的甲氨蝶呤抗性细胞中扩增的二氢叶酸还原酶基因与双微体染色体相关。
Proc Natl Acad Sci U S A. 1979 Nov;76(11):5669-73. doi: 10.1073/pnas.76.11.5669.
8
Gene amplification in methotrexate-resistant mouse cells. V. Intact amplified units can be transferred to and amplified in methotrexate-sensitive mouse L cells.甲氨蝶呤抗性小鼠细胞中的基因扩增。V. 完整的扩增单元可转移至甲氨蝶呤敏感的小鼠L细胞并在其中扩增。
Chromosoma. 1983;88(1):31-41. doi: 10.1007/BF00329501.
9
Novel DNA rearrangements are associated with dihydrofolate reductase gene amplification.新型DNA重排与二氢叶酸还原酶基因扩增相关。
J Biol Chem. 1984 Jul 25;259(14):9127-40.
10
Methotrexate resistance and double minutes in a cell line from the SEWA mouse ascites tumor.
Hereditas. 1982;97(1):123-37. doi: 10.1111/j.1601-5223.1982.tb00720.x.

引用本文的文献

1
Ubiquitous, heritable damage in cell populations that survive treatment with methotrexate.在用甲氨蝶呤治疗后存活的细胞群体中普遍存在的可遗传损伤。
Proc Natl Acad Sci U S A. 1997 Aug 5;94(16):8773-8. doi: 10.1073/pnas.94.16.8773.
2
Altered expression after expansion of a v-erbA transgene in transgenic mice.转基因小鼠中v-erbA转基因扩增后的表达改变。
Transgenic Res. 1995 Nov;4(6):378-87. doi: 10.1007/BF01973756.
3
Gene amplification in methotrexate-resistant mouse cells. V. Intact amplified units can be transferred to and amplified in methotrexate-sensitive mouse L cells.
甲氨蝶呤抗性小鼠细胞中的基因扩增。V. 完整的扩增单元可转移至甲氨蝶呤敏感的小鼠L细胞并在其中扩增。
Chromosoma. 1983;88(1):31-41. doi: 10.1007/BF00329501.
4
Evolution of chromosomal regions containing transfected and amplified dihydrofolate reductase sequences.包含转染和扩增的二氢叶酸还原酶序列的染色体区域的演变。
Mol Cell Biol. 1983 Apr;3(4):699-711. doi: 10.1128/mcb.3.4.699-711.1983.
5
A study of chromosomal changes associated with amplified dihydrofolate reductase genes in rat hepatoma cells and their dedifferentiated variants.一项关于大鼠肝癌细胞及其去分化变体中与二氢叶酸还原酶基因扩增相关的染色体变化的研究。
J Cell Biol. 1984 Aug;99(2):497-502. doi: 10.1083/jcb.99.2.497.
6
Moderate-level gene amplification in methotrexate-resistant Chinese hamster ovary cells is accompanied by chromosomal translocations at or near the site of the amplified DHFR gene.在对甲氨蝶呤耐药的中国仓鼠卵巢细胞中，中等水平的基因扩增伴随着二氢叶酸还原酶（DHFR）基因扩增位点或其附近的染色体易位。
Mol Cell Biol. 1984 Jan;4(1):69-76. doi: 10.1128/mcb.4.1.69-76.1984.
7
Structure of amplified DNA in different Syrian hamster cell lines resistant to N-(phosphonacetyl)-L-aspartate.对N-（膦酰乙酰基）-L-天冬氨酸有抗性的不同叙利亚仓鼠细胞系中扩增DNA的结构
Mol Cell Biol. 1983 Nov;3(11):2076-88. doi: 10.1128/mcb.3.11.2076-2088.1983.
8
Increased dihydrofolate reductase, double minutes and increased nucleolar activation in methotrexate-resistant HeLa cells.甲氨蝶呤耐药的HeLa细胞中，二氢叶酸还原酶增加、双微体增多以及核仁激活增强。
Experientia. 1983 Dec 15;39(12):1394-5. doi: 10.1007/BF01990122.
9
Specific DNA sequence amplification in human neuroblastoma cells.人类神经母细胞瘤细胞中的特定DNA序列扩增
Proc Natl Acad Sci U S A. 1983 Sep;80(18):5724-8. doi: 10.1073/pnas.80.18.5724.
10
Overproduction of a bifunctional thymidylate synthetase-dihydrofolate reductase and DNA amplification in methotrexate-resistant Leishmania tropica.
Proc Natl Acad Sci U S A. 1983 Apr;80(8):2132-6. doi: 10.1073/pnas.80.8.2132.