甲氨蝶呤抗性小鼠细胞中的基因扩增。II. 非二氢叶酸还原酶基因序列的重排和扩增伴随染色体变化。 - Suppr

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超能文献

Gene amplification in methotrexate-resistant mouse cells. II. Rearrangement and amplification of non-dihydrofolate reductase gene sequences accompany chromosomal changes.

作者信息

Bostock C J, Tyler-Smith C

出版信息

J Mol Biol. 1981 Dec 5;153(2):219-36. doi: 10.1016/0022-2836(81)90275-8.

DOI:10.1016/0022-2836(81)90275-8

PMID:6279871

Abstract

摘要

相似文献

Gene amplification in methotrexate-resistant mouse cells. II. Rearrangement and amplification of non-dihydrofolate reductase gene sequences accompany chromosomal changes.甲氨蝶呤抗性小鼠细胞中的基因扩增。II. 非二氢叶酸还原酶基因序列的重排和扩增伴随染色体变化。

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Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes.在不稳定的甲氨蝶呤抗性细胞中扩增的二氢叶酸还原酶基因与双微体染色体相关。

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Gene amplification in methotrexate-resistant mouse cells. V. Intact amplified units can be transferred to and amplified in methotrexate-sensitive mouse L cells.甲氨蝶呤抗性小鼠细胞中的基因扩增。V. 完整的扩增单元可转移至甲氨蝶呤敏感的小鼠L细胞并在其中扩增。

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Novel DNA rearrangements are associated with dihydrofolate reductase gene amplification.新型DNA重排与二氢叶酸还原酶基因扩增相关。

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Methotrexate resistance and double minutes in a cell line from the SEWA mouse ascites tumor.

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Evolution of chromosomal regions containing transfected and amplified dihydrofolate reductase sequences.包含转染和扩增的二氢叶酸还原酶序列的染色体区域的演变。

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A study of chromosomal changes associated with amplified dihydrofolate reductase genes in rat hepatoma cells and their dedifferentiated variants.一项关于大鼠肝癌细胞及其去分化变体中与二氢叶酸还原酶基因扩增相关的染色体变化的研究。

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Moderate-level gene amplification in methotrexate-resistant Chinese hamster ovary cells is accompanied by chromosomal translocations at or near the site of the amplified DHFR gene.在对甲氨蝶呤耐药的中国仓鼠卵巢细胞中，中等水平的基因扩增伴随着二氢叶酸还原酶（DHFR）基因扩增位点或其附近的染色体易位。

Mol Cell Biol. 1984 Jan;4(1):69-76. doi: 10.1128/mcb.4.1.69-76.1984.

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Specific DNA sequence amplification in human neuroblastoma cells.人类神经母细胞瘤细胞中的特定DNA序列扩增

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Overproduction of a bifunctional thymidylate synthetase-dihydrofolate reductase and DNA amplification in methotrexate-resistant Leishmania tropica.

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